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Durable lymph-node expansion improves vaccine responses against tumors

Each one of us has around 600 lymph nodes (LNs) – small, bean-shaped organs that house various types of blood cells and filter lymph fluid – scattered throughout our bodies. ....

United States , Maxence Dellacherie , Hamza Ijaz , Joel Gutierrez Estupinan , Giovanni Bovone , Robertp Pinkas , David Mooney , Shannon Turley , Alberto Elosegui Artola , Donald Ingber , Christina Tringides , Miguel Sobral , Benjamin Freedman , Shawn Kang , Alexander Najibi , Katherine Williams , Harvard Johna Paulson School Of Engineering , Wyss Institute , National Institutes Of Health Cancer Institute , Roche Group , Wyss Institute Founding Core Faculty , Biologically Inspired Engineering , Harvard University , Harvard John , Applied Sciences , Nature Biomedical ,

UCL to co-lead Prostate Cancer UK's new £42m screening trial

UCL academics will co-lead Prostate Cancer UK's new £42m screening trial, which aims to find the best way to screen men for prostate cancer and double the number of lives saved. ....

United Kingdom , City Of , Caroline Moore , Mark Emberton , Matthew Hobbs , Samuel Nelson , Division Of Surgery Interventional Science , Imperial College London , Faculty Of Medical Sciences , Research At Prostate Cancer United Kingdom , Queen Mary University Of London , Care Research , National Institute For Health , National Screening Committee , University College London , Prostate Cancer United Kingdom , National Institute , Professors Mark Emberton , Interventional Science , Queen Mary University , Cancer United Kingdom , Prostate Cancer , Prostate Specific Antigen ,

New vaccine approach shows promise in targeting less variable region of influenza virus

Duke researchers have opened a new avenue in the attack against influenza viruses by creating a vaccine that encourages the immune system to target a portion of the virus surface that is less variable. ....

Zhaochen Luo , Nicholas Heaton , Duke University , National Institute Of Allergy , Duke Regional Biocontainment Laboratory , Science Translational Medicine , National Institute , Infectious Diseases , Immune Response , Immune System ,

Deciphering the role of Th2-multipotent progenitor cells in chronic allergic inflammation

Currently, most therapies for allergic diseases require lifelong treatment. Allergic reactions, characterized by ongoing (type 2) inflammation in response to chronic antigen exposure, underlie many chronic diseases in humans, including asthma, atopic dermatitis, ulcerative colitis and more. ....

United States , Patrick Brennan , Radomir Kratchmarov , Division Of Allergy , Mass General Brigham , Massachusetts General Hospital , Mass Eye , Atopic Dermatitis , Clinical Trial , Ene Expression , Immune Response , Progenitor Cells , Transcription Factors , Ulcerative Colitis ,

Study rethinks immune system strategies to boost vaccine effectiveness

A recent Cell journal review explores key immunological assumptions to enhance our understanding of vaccine design, autoimmune responses, and immune system pathology, aiming to refine intervention strategies and theoretical frameworks in immunology. ....

Natural Killer , Severe Acute Respiratory Syndrome Coronavirus , Immune System , Immune Response , Ars Cov 2 ,