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Boosting CAR-T cell therapies from under the

Boosting CAR-T cell therapies from under the skin

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers, but a large proportion of patients still responds only poorly or not at all to them, calling for new strategies to overcome this challenge. Now, a research team has developed a simple intervention in the form of a biodegradable scaffold material called T-cell enhancing scaffolds (TES) that can be locally injected under the skin and used to restimulate CAR-T cells after their administration. This increased their therapeutic efficacy and significantly curbed tumor growth and prolonged animal survival in an aggressive mouse lymphoma model.

How an AI brain implant helps a stroke survivor communicate

A 20-year-old severely paralyzed bilingual man regained his ability to communicate.

First 'Bilingual' Brain-Reading Device Decodes Spanish and English

New therapy could repair mutations that cause genetic diseases

The beauty is that when we deliver it, gene editing occurs only at the tissue, or the part of the tissue, where we apply the magnetic field