Dundee. We hear about the regions pivotal role in video games and have a visit from nasa. This week, another chance to see click live 2019 in scotland. Enjoy. Im trying to give spencer direction back up to the top, please. We just had a stagger through, which is about three hours behind schedule. Hopefully, its all going to work out in the end when we go live at five oclock. No pressure. Fingers crossed its all going to happen. Were just changing bits. Hope he doesnt mind. Like that . Yeah. Im pleased with that rehearsal. Are you pleased . Kind of, yeah, ijust want these to be in. Theyre in. 0h, theyre in. Its quite nerve racking, at this point, but im excited. Theres a bit of a buzz on, isnt there . Ive been looking forward to it for weeks. Why are you guys here today . Because ijust want to learn, really, see about all the new stuff going on. Are you sure we shouldnt be there already . Trust me, were going to get there on time. But dundee is 500 miles away the trains going to take ho
A microfluidic organ chip model of the human blood-brain barrier for development of brain-targeting therapeutics
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Boosting CAR-T cell therapies from under the
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CAR-T cell therapies are transforming the treatment of previously incurable blood cancers, but a large proportion of patients still responds only poorly or not at all to them, calling for new strategies to overcome this challenge. Now, a research team has developed a simple intervention in the form of a biodegradable scaffold material called T-cell enhancing scaffolds (TES) that can be locally injected under the skin and used to restimulate CAR-T cells after their administration. This increased their therapeutic efficacy and significantly curbed tumor growth and prolonged animal survival in an aggressive mouse lymphoma model.