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A microfluidic organ chip model of the human blood-brain barrier for development of brain-targeting therapeutics

Boosting CAR-T cell therapies from under the

Boosting CAR-T cell therapies from under the skin

CAR-T cell therapies are transforming the treatment of previously incurable blood cancers, but a large proportion of patients still responds only poorly or not at all to them, calling for new strategies to overcome this challenge. Now, a research team has developed a simple intervention in the form of a biodegradable scaffold material called T-cell enhancing scaffolds (TES) that can be locally injected under the skin and used to restimulate CAR-T cells after their administration. This increased their therapeutic efficacy and significantly curbed tumor growth and prolonged animal survival in an aggressive mouse lymphoma model.

Microfluidic Organ Chip Models Human Cervix, Boosts Women's Health

Using static electricity, RoboBees can land and stick to surfaces

New system extends the lives of flying microrobots