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Study on largest genetic risk factor for Alzh

<p>Scientists at Gladstone Institutes have discovered that APOE4-producing neurons release an immune signaling molecule called HMGB1 at much higher rates than neurons producing other APOE variants. Upon release, HMGB1 activates brain immune cells called microglia, which then trigger inflammation and the degeneration of neurons.</p>
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Mission Bay , United States , San Francisco , Oscar Yip , Nicole Koutsodendris , Yanxia Hao , Seo Yeon Yoon , Misha Zilberter , Patrick Arriola , Michela Traglia , Maxiner Nelson , Reuben Thomas , Antara Rao , Yadong Huang , Aayushi Agrawal , Jessica Blumenfeld , Yung Hua Wang , Joo Kim , Brian Grone , Gabaeron Inc , University Of California , Method Of Research , National Institutes Of Health , Gladstone Institutes , Cell Reports , Gladstone Investigator ,

Treating tough tumors by exploiting their iron 'addiction'

Researchers at the University of California, San Francisco, have successfully leveraged an FDA-approved drug to halt growth of tumors driven by mutations ....

San Francisco , United States , Adam Olshen , James Korkola , Michael Evans , Honglin Jiang , Eric Collisson , Bryan Muir , Ryan Gonciarz , Iwei Yeh , Spencer Behr , Byron Hann , Adam Renslo , University Of California , Oregon Health Sciences University , Helen Diller Family Comprehensive Cancer Center , Experimental Medicine , Diller Family Comprehensive Cancer , Cancer Drug , New Drug Combinations , Ning Zhao , Yung Hua Wang , Oregon Health ,

Treating tough tumors by exploiting their iron 'addiction' | University of California

UCSF researchers tame notorious KRAS-mutated cancers without harming healthy cells. ....

Adam Olshen , James Korkola , Michael Evans , Bryan Muir , Ryan Gonciarz , Iwei Yeh , Spencer Behr , Byron Hann , Oregon Health Sciences University , Ning Zhao , Yung Hua Wang , Oregon Health ,

Treating tough tumors by exploiting their iron 'addiction'

Treating tough tumors by exploiting their iron 'addiction'
miragenews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from miragenews.com Daily Mail and Mail on Sunday newspapers.

San Francisco , United States , Adam Olshen , James Korkola , Honglin Jiang , Michael Evans , Eric Collisson , Bryan Muir , Iwei Yeh , Ryan Gonciarz , Spencer Behr , Byron Hann , Adam Renslo , Oregon Health Sciences University , University Of California , Helen Diller Family Comprehensive Cancer Center , Experimental Medicine , Diller Family Comprehensive Cancer , Cancer Drug , Ning Zhao , Yung Hua Wang , Oregon Health ,

Novel imaging agent identifies biomarker for iron-targeted cancer therapies

Novel imaging agent identifies biomarker for iron-targeted cancer therapies
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

Stanford University , United States , San Francisco , Pavithra Viswanath , Davide Ruggero , Nima Hooshdaran , Ying Chu Chen , Rebecca Maxey , Michael Evans , Ryank Muir , Michael John Evans , Adamr Renslo , Yangjie Huang , Youngho Seo , Bryan Muir , Michaelj Evans , Adam Renslo , Junnian Wei , University Of California , Journal Of Nuclear Medicine , National Institutes Of Health , Media Center , Tatara Therapeutics Inc , Prostate Cancer Program , American Cancer Society , Measuring Tumoral Ferrous Iron ,