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Beyond Increased Risk: APOE4 a Direct Cause of AD?

Two copies of APOE4 may be more than just a risk factor for AD; the pair may cause the disease in 15%-20% of cases. ....

San Francisco , United States , United Kingdom , Comunidad Autonoma De Cataluna , David Curtis , Yuko Hara , Sant Pau , Juan Fortea , Paul Mathews , Yadong Huang , Reisa Sperling , Memory Unit Of The Neurology Department , University Of California , Alzheimer Research , Alzheimer Drug Discovery Foundation , Genetics Institute At University Of College London , University Of Wisconsin , National Alzheimer Coordinating Center , Memory Unit , Neurology Department , Nature Medicine , National Alzheimer , Coordinating Center , Sterling Johnson , Massachusetts General Hospital , United Kingdom Dementia Research Institute Centre ,

Alzheimer's Type Identified That Involves Gene Variant Carried by 2% of Population

Alzheimer's Type Identified That Involves Gene Variant Carried by 2% of Population
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United States , Comunidad Autonoma De Cataluna , Sant Pau , Zherui Liang , Juan Fortea , Qin Xu , Yadong Huang , Us National Alzheimer Coordinating Center , Sant Pau Research Institute , Barcelona Supercomputing Center , Pasqual Maragall Foundation , Coordinating Center , Alberto Lle , Gladstone Institutes ,

Alzheimer's Variant May Cause Distinct Form of the Disease

Almost all <em>APOE4</em> homozygotes develop Alzheimer's disease ....

Comunidad Autonoma De Cataluna , United States , Juan Fortea , Judy George , Sant Pau , Reisa Sperling , Yadong Huang , National Alzheimer Coordinating Center , University Of California San Francisco , National Alzheimer , Coordinating Center , California San Francisco , Medpage Today ,

First Whole-Genome Sequencing of PSP Nets Six New Risk Loci

First Whole-Genome Sequencing of PSP Nets Six New Risk Loci
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United States , New York , University Of Pennsylvania , United Kingdom , San Francisco , University Hospital , Lance Johnson , Daniel Geschwind , Shui Wang , Los Angeles , James Rowe , Timothy Chang , Yadong Huang , David Holtzman , Chelsea Weidman Burke , Gerard Schellenberg , National Institute On Aging Alzheimer Disease Sequencing , Lesley Golden Of The University Kentucky , Washington University , University Of Cambridge , University Of California , Ludwig Maximilians University Hospital , Wan Ping Lee , Dennis Dickson , Mayo Clinic , National Institute ,

How CRISPR gene editing could help treat Alzheimer's

Some researchers hoping that gene-editing technology can conquer forms of Alzheimer’s caused by genetic mutations. Some researchers hoping that gene-editing technology can conquer forms of Alzheimer’s caused by genetic mutations. ....

San Diego , United States , San Francisco , City Of , United Kingdom , Subhojit Roy , Martin Ingelsson , Yadong Huang , Gerold Schmitt Ulms , Simon Fraser Science Photo Library , University Of Edinburgh , University Of Toronto , Us National Institutes Of Health , Drug Administration , University Of California , Science Photo , Tara Spires Jones , Nature Medicine , Gladstone Institutes , Molecular Therapy Nucleic ,