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Learning how to control HIV from African geno

A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. An international effort co-led by EPFL, Canada’s National Microbiology Laboratory, and Imperial College London, it paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities. ....

Stanford University , United States , Noord Holland , Comunidad Autonoma De Cataluna , San Francisco , South Africa , Free State , Eastern Cape , Reggio Emilia , Emilia Romagna , City Of , United Kingdom , Mariannek Degorter , Erico Johnson , Davidb Goldstein , Segun Fatumo , Miriam Walter , Ayeshaa Motala , Andrea Cossarizza , Jamesj Goedert , Gordon Dougan , Cheryla Winkler , Stevenm Wolinsky , Cristina Pomilla , Isobel Jarvis , Paolo Angelino ,

Cardiac Antigen Identified as Mechanism for Heart Complication

(HEALTH NEWS) Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare — affecting less than 1% of patients given the immunotherapy — the mortality rate is nearly 50%.
Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation.
The researchers discovered that T-cells recognizing the cardiac antigen α-myosin are the mechanism for this . ....

United States , Wouter Meijers , Yueli Zhang , Ayaka Sugiura , Javid Moslehi , Xiaopeng Sun , Warren Tai , Susan Opalenik , Juan Qin , Jeffrey Rathmell , Jamesc Bradford Jr , Abigail Toren , Margaret Axelrod , Jamesp Allison , Brandie Taylor , Elie Tannous , Douglas Johnson , Elizabeth Phillips , Ann Hanna , Kaushik Amancherla , Simon Mallal , P Brent Ferrell , Vanderbilt Ingram Cancer Center , Fund In Melanoma Cancer Research , National Institutes Of Health , Md Anderson Cancer Center ,