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Vulnerability found in immunotherapy-resistant triple-negative breast cancer

Vulnerability found in immunotherapy-resistant triple-negative breast cancer
medicalxpress.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from medicalxpress.com Daily Mail and Mail on Sunday newspapers.

Justin Balko , Susan Opalenik , Brian Lehmann , Vandana Abramson , Paula Gonzalez Ericsson , Elizabeth Wescott , Brandiec Taylor , Jennifer Pietenpol , Melinda Sanders , Xiaopeng Sun , Ann Hanna , Balko Lab , Ingram Associate Professor Of Cancer Research , Researchers At Vanderbilt Ingram Cancer Center , Vanderbilt Ingram Cancer Center , Cancer Discovery , Ingram Associate Professor , Cancer Research ,

Druggable Target Discovered in Immunotherapy-Resistant Triple-Negative Breast Cancer

Druggable Target Discovered in Immunotherapy-Resistant Triple-Negative Breast Cancer
insideprecisionmedicine.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from insideprecisionmedicine.com Daily Mail and Mail on Sunday newspapers.

Justin Balko , Brandiec Taylor , Peddalanka Ramesh Babu Getty , Xiaopeng Sun , A Natural Killer Group , Vanderbilt Ingram Cancer Center , Balko Lab , Cancer Research , Peddalanka Ramesh , Cancer Discovery , Natural Killer Group , Mahor Histocompatibility Complex ,

Cardiac Antigen Identified as Mechanism for Heart Complication

(HEALTH NEWS) Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare — affecting less than 1% of patients given the immunotherapy — the mortality rate is nearly 50%.
Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation.
The researchers discovered that T-cells recognizing the cardiac antigen α-myosin are the mechanism for this . ....

United States , Wouter Meijers , Yueli Zhang , Ayaka Sugiura , Javid Moslehi , Xiaopeng Sun , Warren Tai , Susan Opalenik , Juan Qin , Jeffrey Rathmell , Jamesc Bradford Jr , Abigail Toren , Margaret Axelrod , Jamesp Allison , Brandie Taylor , Elie Tannous , Douglas Johnson , Elizabeth Phillips , Ann Hanna , Kaushik Amancherla , Simon Mallal , P Brent Ferrell , Vanderbilt Ingram Cancer Center , Fund In Melanoma Cancer Research , National Institutes Of Health , Md Anderson Cancer Center ,