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"Obesity Paradox" of Cancer Immunotherapy Response Linked to Immune Checkpoint Protein on Macrophages

"Obesity Paradox" of Cancer Immunotherapy Response Linked to Immune Checkpoint Protein on Macrophages
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Jeffrey Rathmell , Jackie Bader , Vanderbilt University Medical , Vanderbilt Center , Vanderbilt University Medical Center Led , Cornelius Vanderbilt Professor ,

Obesity-cancer connection discovery suggests strategies for improving immunotherapy

Immune system cells called macrophages play an unexpected role in the complicated connection between obesity and cancer. The findings provide a mechanistic explanation for how obesity can contribute to both increased cancer risk and enhanced responses to immunotherapy. ....

United States , Jackie Bader , Jeffrey Rathmell , American Association For Cancer Research , Vanderbilt Center , National Institutes Of Health , Vanderbilt Incyte Alliance , Cornelius Vanderbilt Professor , National Institutes , American Association , Cancer Research ,