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TORL BioTherapeutics Announces $158 Million Oversubscribed Series B-2 Financing to Advance the Clinical Development of its Novel Antibody-Drug Conjugate (ADC) Oncology Pipeline

$158M Series B-2 Financing led by Deep Track Capital, with new participation from leading global biotechnology investors including RA Capital Management,.

Dave licataVince ruizRibociclib kisqaliMark allesPalbociclib ibranceDennis slamonPerceptive xontogeny venture fundSlamon research laboratoryBristol myers squibbDivision of hematology oncologyRoth zabelCrandon lawDavid geffen school of medicineDeep track capitalPerceptive advisorsAvidity partners

How is Metastatic Breast Cancer Treated?

How is Metastatic Breast Cancer Treated?
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United statesBeverly hillsOrserdu elacestrantAlpelisib piqrayEverolimus afinitorTalazoparib talzeenaKelly mccannTucatinib tukysaPembrolizumab keytrudaPalbociclib ibrancePertuzumab perjetaNeratinib nerlynxTrastuzumab herceptinRibociclib kisqaliAbemaciclib verzeniosOlaparib lynparza

Ribociclib regimen provides durable benefit, reduces recurrence in breast cancer subgroup

Ribociclib regimen provides durable benefit, reduces recurrence in breast cancer subgroup
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United statesSan antonioBymark leiserMindy valcarcelGabrieln hortobagyiRibociclib kisqaliUniversity of texas md anderson cancer centerSan antonio breast cancerSan antonio breast cancer symposiumCancer center

Ribociclib Lowers Risk of Disease Recurrence by 25% for Early Breast Cancer

Ribociclib (Kisqali) demonstrated a 26% risk reduction in distant disease-free survival and a 28% risk reduction in recurrence-free survival in patients with HR+/HER2- early breast cancer.

United statesShreeram aradhyeDennisj slamonRibociclib kisqaliTranslational research in oncologyAmerican society of clinical oncology annual meetingClinical translational researchGlobal drug developmentClinical oncology annualTranslational researchCalifornia los angelesJonsson comprehensive cancer center

Ribociclib/Fulvestrant Combo Generates PFS Improvement in Metastatic Breast Cancer

Ribociclib plus switch endocrine therapy induced a statistically significant progression-free survival benefit compared with placebo plus switch endocrine therapy in patients with hormone receptor–positive, HER2-negative, metastatic breast cancer.

United statesKevin kalinskyRibociclib kisqaliWinship cancer instituteEmory universitySwitch endocrine therapyMaintain trialHormone receptor positive breast cancerHer2 negative breast cancerBreast cancerJournal of clinical oncology