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A pre-emptive approach to treating leukaemia relapse

The monitoring of measurable residual disease (MRD), medication and low-dose chemotherapy is helping patients live longer with acute myeloid leukaemia (AML). ....

Nemes Laszlo , Peter Mac , Andrew Wei , Lymphoma Group , Peter Maccallum Cancer Centre Mac , Peter Maccallum Cancer Centre , Ing Soo Tiong , Clinical Oncology , Royal Melbourne Hospital , Australasian Leukaemia , Peter Maccallum Cancer Centre , Peter Mac , Measurable Residual Disease , Acute Myeloid Leukaemia , Journal Of Clinical Oncology ,

rPFS and cPFS May Act as Surrogate OS End Points in Phase 3 mHSPC Clinical Trials

Radiographic and clinical progression-free survival may be surrogates for overall survival in hormone-sensitive prostate cancer clinical trials. ....

North Carolina , United States , Jamesb Duke , Susan Halabi , Duke Cancer Institute In Durham , Division Of Biostatistics , Distinguished Professor , Duke Cancer Institute , Surrogacy Analysis , Journal Of Clinical Oncology , Progression Free Survival , Overall Survival , Hormone Sensitive Prostate Cancer , Clinical Trials , Rpfs And Cpfs Are Surrogates For Os , Phase 3 Clinical Trials , Testosterone Suppression Based Treatment Strategies ,

Adding Pemetrexed to Cisplatin Does Not Result in Survival Benefit Over Vinorelbine in NSCLC

Adjuvant treatment with the chemotherapy doublet of pemetrexed and cisplatin did not lead to a significant improvement in overall survival compared with vinorelbine plus cisplatin in patients with stage II to IIIA nonsquamous non–small cell lung cancer. ....

Patients With Egfr Mutated Advanced Non Small Cell Lung Cancer , Journal Of Clinical Oncology , Phase 3 Jipang Study Umin000006737 ,

Second-Line Trastuzumab Plus Ramucirumab/Paclitaxel Elicits Activity in HER2+ Gastric/GEJ Cancer

Trastuzumab plus ramucirumab and paclitaxel yielded promising efficacy and a manageable safety profile among patients with previously treated HER2-positive advanced gastric/gastroesophageal junction cancer. ....

South Korea , Republic Of Korea , Trastuzumab Herceptin , Gastric Cancer , Gastroesophageal Junction Adenocarcinoma , Trastuzumab Deruxtecan , Her2 Positive Gastric Or Gastroesophageal Junction Gej Cancer , Trastuzumab Containing Regimen , Journal Of Clinical Oncology , The Phase 1 2 Her Ram Study Nct04888663 ,

Five-year survival rate for children with acute lymphatic leukemia has increased: Study

The study results of the ALL-11 treatment protocol, led by researchers at the Princess Maxima Center, were published in the scientific Journal of Clinical Oncology. ....

Rob Pieters , Princess Maxima Center , Paediatric Cancer , Cute Lymphatic Leukaemia , Treatment Protocol , Princess Maxima Center , Survival Rates , Quality Of Life , Scientific Discoveries , Ll 11 Treatment Protocol , Journal Of Clinical Oncology , Five Year Survival Rate , Research Study , Utch Youngsters , Odified Treatment Procedures , Disease Recurrence , Ggressive Form Of Leukemia , Karos Abnormality , Aintenance Phase Chemotherapy , Risk Reduction , Intensive Treatment , Na Abnormality , Side Effects , Heart Damage , Cure Rate , Down Syndrome ,