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Zanidatamab exhibits 'promising' efficacy in advanced HER2-positive biliary tract cancer

CHICAGO — Zanidatamab exhibited durable antitumor activity among patients with previously treated advanced HER2-amplified biliary tract cancer, according to results of the phase 2B HERIZON-BTC-01 study presented at ASCO Annual Meeting.More than half of patients who received zanidatamb (Jazz Pharmaceuticals/Zymeworks) monotherapy survived at least a year and median OS exceeded 15 months. ....

United States , Bymark Leiser , Mindy Valcarcel , University Of Texas Md Anderson Cancer Center , Jazz Pharmaceuticals Zymeworks , Jazz Pharmaceuticals , Shubham Pant , Cancer Center ,

Trastuzumab deruxtecan improves PFS in pretreated breast cancer

CHICAGO — Trastuzumab deruxtecan extended PFS compared with standard chemotherapy for certain patients with pretreated breast cancer, according to findings presented at ASCO Annual Meeting.The analysis — which included patients with hormone receptor-positive, HER2-low or HER2-ultralow metastatic breast cancer that progressed after endocrine therapy — also showed considerably ....

United States , Giuseppe Curigliano , Mindy Valcarcel , Daiichi Sankyo , Bymark Leiser , University Of Milan , European Institute Of Oncology , European Institute ,

High-deductible health plans linked to shorter survival for cancer survivors

CHICAGO — High-deductible health plans appeared associated with shorter survival among cancer survivors, according to results of a nationwide population-based analysis presented at ASCO Annual Meeting.The findings suggest high-deductible health plans may create a financial disincentive for cancer survivors that prevents them from seeking necessary medical care, according to Justin Barnes, ....

United States , Justin Barnes , Mindy Valcarcel , Bymark Leiser , National Death Index , American Cancer Society , Washington University School Of Medicine , National Health Interview , Washington University School , Health Interview Survey ,

Findings highlight need to improve prior authorization process for cancer pain management

CHICAGO — A review of more than 1,700 prior authorization requests related to pain medication for people with cancer showed the vast majority ultimately got approved.However, chart reviews documented uncontrolled pain and unmanageable side effects for many patients whose requests had been denied. ....

United States , Fumiko Chino , Mindy Valcarcel , Bymark Leiser , Memorial Sloan Kettering Cancer Center , Healio Women , Oncology Peer Perspective Board , Capitol Hill ,

PDMP mandates linked to reductions in opioid analgesics for people dying of cancer

CHICAGO — Comprehensive prescription drug monitoring program mandates appeared associated with a moderate reduction in the number of opioid analgesics dispensed to people dying of cancer, according to study results.Reductions were two to three times higher among non-Hispanic Black and Asian/Pacific Islander decedents than non-Hispanic white decedents, findings presented at ASCO Annual ....

United States , Bymark Leiser , Yuhua Bao , Hispanic Black , Pacific Islander , Weill Cornell Medicine ,