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Cardiac Antigen Identified as Mechanism for Heart Complication

(HEALTH NEWS) Myocarditis is a complication that can occur in cancer patients treated with immune checkpoint inhibitors. Although the adverse event is rare — affecting less than 1% of patients given the immunotherapy — the mortality rate is nearly 50%.
Now, researchers from Vanderbilt-Ingram Cancer Center have identified the mechanism for the deadly heart inflammation.
The researchers discovered that T-cells recognizing the cardiac antigen α-myosin are the mechanism for this . ....

United States , Wouter Meijers , Yueli Zhang , Ayaka Sugiura , Javid Moslehi , Xiaopeng Sun , Warren Tai , Susan Opalenik , Juan Qin , Jeffrey Rathmell , Jamesc Bradford Jr , Abigail Toren , Margaret Axelrod , Jamesp Allison , Brandie Taylor , Elie Tannous , Douglas Johnson , Elizabeth Phillips , Ann Hanna , Kaushik Amancherla , Simon Mallal , P Brent Ferrell , Vanderbilt Ingram Cancer Center , Fund In Melanoma Cancer Research , National Institutes Of Health , Md Anderson Cancer Center ,

GO2 Foundation for Lung Cancer Expands Scientific Leadership Board in Effort to Double Five-Year Survival Rate by 2025

GO2 Foundation for Lung Cancer Expands Scientific Leadership Board in Effort to Double Five-Year Survival Rate by 2025
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