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CRISPR-based mapping uncovers 'switches' for immune genes central to health

Healthy T cells are the foundation of a balanced immune system. They can spring into action to fight off infections or cancer, but keep from becoming so activated that they hurt the very cells they re meant to protect, as is the case in autoimmune diseases. ....

Codyt Mowery , Cody Mowery , Alex Marson , Katie Pollard , University Of California San Francisco , Institute Of Genomic Immunology , Nature Genetics , Gladstone Institutes , Gladstone Senior Investigator Alex Marson , Genomic Immunology , California San Francisco , Gladstone Senior Investigator Katie Pollard , Parker Institute ,

Lego-Like Gene Editing Tool Lets Researchers Improve Cancer Immunotherapy

Scientists used a new method to screen 10,000 combinations of gene edits in immune cells engineered to fight cancer ....

San Francisco , United States , Stanford School , Mission Bay , Eric Shifrut , Torin Yamamoto , Barbara Bakar , Raymund Bueno , Yan Yi Chen , Elena Radutzky , Peixin Amy Chen , Julie Langelier , Cheol Kim , Justin Eyquem , Tobias Feuchtinger , Franziska Blaeschke , Chan Zuckerberg Biohub , Williama Nyberg , Cody Mowery , Ansuman Satpathy , Ralf Schmidt , Theodore Roth , Wenxi Zhang , Andyy Chen , Ruby Yu , Bence Daniel ,

Lego-Like Gene Editing Tool Lets Researchers Improve Cancer Immunotherapy

/PRNewswire/ In recent years, scientists have used gene modification technologies to reprogram immune cells into therapeutics that can attack cancers. But. ....

Stanford School , United States , Mission Bay , San Francisco , Alex Marson , Bence Daniel , Elena Radutzky , Ansuman Satpathy , Yan Yi Chen , Andyy Chen , Theodore Roth , Ralf Schmidt , Julia Carnevale , Zhongmei Li , Cody Mowery , Williama Nyberg , Tobias Feuchtinger , Chan Zuckerberg Biohub , Torin Yamamoto , Peixin Amy Chen , Franziska Blaeschke , Justin Eyquem , Cheol Kim , Danielb Goodman , Wenxi Zhang , Barbara Bakar ,

How Obesity Can Rewire Immune System and Response to Immunotherapy – and How to Change That

How Obesity Can Rewire Immune System and Response to Immunotherapy – and How to Change That
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United States , Salk Institute , New South Wales , San Francisco , Caroline Whitty , Michael Peters , Marlys Fassett , Emma Guttman Yassky , Sarah Gayer , Zhongmei Li , Richard Gallo , Wandi Zhu , Laura Crotty Alexander , Noah Berger Sagar Bapat , Alex Marson , Zewen Jiang , Ronald Evans , Ruth Yu , Sagar Bapat , Christopher Liddle , Yuqiong Liang , Jamie Sturgill , Xin Ren , Vinh Nguyen , Jae Myoung Suh , Annette Atkins ,

How Obesity Can Rewire the Immune System and the Response to Immunotherapy--and How to Change That

/PRNewswire/ When mice with atopic dermatitis a common type of allergic skin inflammation are treated with drugs that target the immune system, their. ....

United States , Salk Institute , New South Wales , San Francisco , Chan Zuckerberg Biohub , Caroline Whitty , Michael Peters , Marlys Fassett , Emma Guttman Yassky , Sarah Gayer , Zhongmei Li , Richard Gallo , Wandi Zhu , Laura Crotty Alexander , Julie Langelier , Alex Marson , Zewen Jiang , Ronald Evans , Sagar Bapat , Ruth Yu , Christopher Liddle , Yuqiong Liang , Xin Ren , Jamie Sturgill , Vinh Nguyen , Jonas Salk ,