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CRISPR-based mapping uncovers 'switches' for immune genes central to health

Healthy T cells are the foundation of a balanced immune system. They can spring into action to fight off infections or cancer, but keep from becoming so activated that they hurt the very cells they re meant to protect, as is the case in autoimmune diseases.

Codyt-mowery
Cody-mowery
Alex-marson
Katie-pollard
University-of-california-san-francisco
Institute-of-genomic-immunology
Nature-genetics
Gladstone-institutes
Gladstone-senior-investigator-alex-marson
Genomic-immunology
California-san-francisco
Gladstone-senior-investigator-katie-pollard

Racing modified cells against each other in humans may be the next step in gene therapies

The next evolution of gene therapies may involve pitting T cells with different modifications against one another in a “race” inside a human to determine which edits produce the best results against a tumor, an expert panel predicted. Researchers across the globe have discovered dozens of genes that could be targeted to make T cells more durable and effective in tumor

Marcelav-maus
Mindy-valcarcel
Alex-marson
Byjosh-friedman
Stanford-university
Friends-of-cancer-research
Parker-institute-for-cancer-immunotherapy
University-of-pennsylvania
Cancer-center
Institute-of-genomic-immunology
Cancer-research
Parker-institute

Age-associated CD4+ T cells with B cell-promoting functions are regulated by ZEB2 in autoimmunity

Age-associated CD4+ T cells with B cell-promoting functions are regulated by ZEB2 in autoimmunity
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Stanford
Izumisawa
Hokkaido
American

Global Gene Synthesis Industry Set to Surpass US$4.5 Billion, Fueled by a Robust 19.2% CAGR by 2033 | According to Latest FMI Report

Global Gene Synthesis Industry Set to Surpass US$4.5 Billion, Fueled by a Robust 19.2% CAGR by 2033 | According to Latest FMI Report
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