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Nelisiwe Msomi Share A new HIV treatment has been found to cause weight gain compared to the old version Increased cholesterol and fat levels were found in the blood of patients who made the switch Experts recommend that an individualised approach to HIV medication should be taken People who changed their HIV treatment to tenofovir alafenamide (TAF) gained 1.7 kg more than individuals who remained on tenofovir disoproxil fumarate (TDF), who gained only 0.7 kg during an 18 month observation period. Tenofovir is used as part of standard HIV treatment. TDF was previously widely used and has been linked to renal side effects and bone loss. TAF is the new variant that replaced TDF and has been found to have fewer side effects. ....
Certain HIV Meds May Trigger Weight Gain webmd.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from webmd.com Daily Mail and Mail on Sunday newspapers.
URL goes live when the embargo lifts Switching from antiretroviral therapy (ART) containing tenofovir disoproxil fumarate (TDF) to ART containing tenofovir alafenamide (TAF) is associated with increased risk for significant weight increases, obesity, and rising blood lipid levels in people living with HIV. In contrast to most previous studies that were performed among treatment-naive patients, the changes in weight in the present study could not be attributed to better health due to starting HIV treatment as the patients studied were already taking ART with TDF for 6 months or longer. These findings from a cohort study are published in Annals of Internal Medicine. ....
Credit: Insel Gruppe In Switzerland about 17 000 people are living with an HIV infection, worldwide there are about 38 million. Today, the disease can be treated so successfully that a normal life can be ensured to a great extent. However, weight increases are often observed at the beginning of HIV therapy due to adaptations of the metabolism, which are part of a successful therapy. Therefore, body weight control plays an important role in HIV therapy. It is important, for example, to avoid metabolic problems that can lead to heart attacks or diabetes over the long term. Tenofovir is the drug used as part of the standard HIV therapies. The previously, widely used TDF-based therapy (tenofovir disoproxil fumarate, TDF) has been associated with renal side effects and bone loss. It was therefore steadily replaced with a new variant, TAF-based therapy (tenofovir alafenamide), which was associated with fewer side effects. The study presented here explores evidence of excessive ....