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A study on almost four thousand people of African descent has identified a gene that acts as natural defense against HIV by limiting its replication in certain white blood cells. An international effort co-led by EPFL, Canada’s National Microbiology Laboratory, and Imperial College London, it paves the way for new treatment strategies and underscores the importance of studying diverse ancestral populations to better address their specific medical needs and global health disparities. ....
Nelisiwe Msomi Share A new HIV treatment has been found to cause weight gain compared to the old version Increased cholesterol and fat levels were found in the blood of patients who made the switch Experts recommend that an individualised approach to HIV medication should be taken People who changed their HIV treatment to tenofovir alafenamide (TAF) gained 1.7 kg more than individuals who remained on tenofovir disoproxil fumarate (TDF), who gained only 0.7 kg during an 18 month observation period. Tenofovir is used as part of standard HIV treatment. TDF was previously widely used and has been linked to renal side effects and bone loss. TAF is the new variant that replaced TDF and has been found to have fewer side effects. ....