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Researchers find a genetic solution to ensure sorghum stands firm 3 Apr, 2021 07:00 PM 3 minutes to read Professor David Jordan views sorghum crop at the Gatton Research Facility. Photo / Supplied The Country After decades of study, University of Queensland researchers have identified a genetic solution to the problem of sorghum lodging and falling down. Lodging was when the stems of plants carrying high grain yields were weakened by loss of water, Professor David Jordan from UQ s Queensland Alliance for Agriculture and Food Innovation explained. The problem affects 10 per cent of sorghum crops each year. Losing a bumper grain crop because plants fall over is heartbreaking for growers and undermines efforts to increase production to improve food security, Jordan said. ....
First-of-its-kind study identifies 13 new Alzheimer’s disease genes In the first study to use whole genome sequencing (WGS) to discover rare genomic variants associated with Alzheimer s disease (AD), researchers have identified 13 such variants (or mutations). In another novel finding, this study establishes new genetic links between AD and the function of synapses, which are the junctions that transmit information between neurons, and neuroplasticity, or the ability of neurons to reorganize the brain s neural network. These discoveries could help guide development of new therapies for this devastating neurological condition. Researchers at Massachusetts General Hospital (MGH), the Harvard T. H. Chan School of Public Health, and Beth Israel Deaconess Medical Center report these findings in ....
UCI-led team to address health impacts of adverse childhood experiences using precision medicine A collaborative team centered in the University of California, Irvine (UCI) and including Children s Hospital Orange County (CHOC) and Chapman University (CU) has been awarded a three-year grant totaling in excess of $2.3 million, to address the health impacts of adverse childhood experiences (ACEs) using precision medicine. Announced by the California Governor s Office of Planning & Research, in partnership with the Office of the California Surgeon General, the award is part of the California Initiative to Advance Precision Medicine (CIAPM). The research project will begin May 2021. Led by Tallie Z. Baram, MD, PhD, Bren Distinguished Professor and director of the Conte Center at UCI, the UCI, CHOC and CU team has established two goals. The first is to identify the degree to which unpredictability of early life experiences interacts with established ACEs to influence children s ....
Specific gene may play a causal role in heart disease independent of cholesterol levels High cholesterol is the most commonly understood cause of atherosclerosis, a hardening of the arteries that raises the risk of heart attack and stroke. But now, scientists at Washington University School of Medicine in St. Louis have identified a gene that likely plays a causal role in coronary artery disease independent of cholesterol levels. The gene also likely has roles in related cardiovascular diseases, including high blood pressure and diabetes. The study appears March 24 in the journal Science Translational Medicine. Studying mice and genetic data from people, the researchers found that the gene called SVEP1 makes a protein that drives the development of plaque in the arteries. In mice, animals missing one copy of SVEP1 had less plaque in the arteries than mice with both copies. The researchers also selectively reduced the protein in the arterial walls of mice, ....