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New Brigham–Wyss Diagnostic Accelerator could enable fast creation of diagnostic technologies

New Brigham–Wyss Diagnostic Accelerator could enable fast creation of diagnostic technologies
Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Boston s Brigham and Women Hospital (Brigham) announce their newly founded Diagnostic Accelerator (Brigham-Wyss DxA). By combining the institutions broad clinical and multi-disciplinary bioengineering expertise, the Brigham-Wyss DxA will enable the fast creation of diagnostic technologies through deep collaborations in a process driven by previously unmet needs.
The Brigham-Wyss DxA presents a new type of research collaboration with the potential to significantly compress the timeframe for introducing new diagnostic technologies specifically developed to solve high-value clinical problems. The collaborators plan to achieve this through a formal process by which unmet diagnostic challenges are identified by the Brigham clinical community, effectively matched with highly appropriate technolo ....

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FIND Cell is a new tool that digitizes cell culture to enable reproducible biomedical science

FIND Cell is a new tool that digitizes cell culture to enable reproducible biomedical science
New cloud based software platform reduces research costs and improves speed and reliability
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NEW YORK, May 19, 2021 /PRNewswire/ Lack of reproducibility is a critical problem in biomedical science, wasting both time and billions of dollars every year. The Correspondence
Tracking cell lineages improves research reproducibility , published today in
Nature Biotechnology, lays the scientific foundation for a brand-new software platform called
FIND Cell; a unique tool that aims to improve reproducibility of cell-based science.
FIND Cell (available at https://findgen.bio/) integrates daily cell line tracking with genetic verification. It enables scientists to digitize, organise, verify, and find their cell culture related information – which is critical for biomedical research. ....

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Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer
In a new resource for the scientific community, published today in
Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.
With this technology, they profile changes in genome organization and create a large-scale atlas of how loss of individual chromatin-altering enzymes impacts the human genome. The new method harnesses the programmability of the gene editing system CRISPR to knock-out nearly all chromatin-related genes in parallel, offering researchers deeper insights into the role of DNA accessibility in cancer and in rare diseases involving chromatin. ....

New York , United States , New York University , Neville Sanjana , Noa Liscovitch Brauer , Jay Shendure , Emily Henderson , Sanjana Lab , Innovation Technology Lab , York Genome Center , University Of Washington , Grossman School Of Medicine , Study Co , York University , Nature Biotechnology , New York Genome Center , Study Co Author , Postdoctoral Fellow , Antonino Montalbano , Core Faculty Member , Assistant Professor , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , புதியது யார்க் பல்கலைக்கழகம் , நெவில் சஞ்சனா , ஜெய் ஷெண்டுரே ,

Single-cell CRISPR technology deciphers role of chromatin accessibility in cancer

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IMAGE: CRISPR-sciATAC is a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. The new method harnesses the programmability of the gene editing system.
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Credit: Sanjana Lab of New York Genome Center and NYU
NEW YORK, NY (April 29, 2021) - In a new resource for the scientific community, published today in
Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide. With this technology, they profile changes in genome organization and create a large-scale atlas of how loss of individual chromatin-altering enzymes impacts the human genome. The new method harnesses the programmability of the gene ed ....

New York , United States , Memorial Sloan Kettering Cancer Center , Rockefeller University , New York University , Cold Spring Harbor Laboratory , Hospital For Special Surgery , American Museum Of Natural History , Columbia University , Neville Sanjana , Noa Liscovitch Brauer , Karen Zipern , Jay Shendure , Sanjana Lab , York Genome Center , Rutgers Cancer Institute Of New Jersey , University Of Washington , Grossman School Of Medicine , Roswell Park Cancer Institute , York University , Hackensack Meridian Health , York Stem Cell Foundation , Northwell Health , Albert Einstein College Of Medicine , Princeton University , Stony Brook University ,

Meet the Team: Patricia Cortes, Human Capital Initiative | Global Development Policy Center

Meet the Team: Patricia Cortes, Human Capital Initiative | Global Development Policy Center
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