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Northwestern scientists explore impacts of genomic variation in disease in NIH project

Falling in love with dramas for Chinese Valentine's Day | Lifestyle

Falling in love with dramas for Chinese Valentine's Day | Lifestyle
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Discovery of new type of stem cells leads to $2.3 million grant


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WEST LAFAYETTE, Ind. When muscle is damaged, resident stem cells mediate the repair of the injured tissue. At the same time, circulating immune cells race to the site to aid the repair.
The presence of these infiltrating immune cells at injury sites raises questions about their role in coordinating with muscle stem cells to build or regenerate muscle tissue.
Shihuan Kuang, a Purdue professor of animal sciences, has identified a previously unknown subset of muscle stem cells, which he has dubbed “immunomyoblasts,” that have both muscle stem cell and immune cell properties and may shed light on how those cells interact. ....

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Gene mutations linked to worse leukemia outcomes in Hispanic and Latino children


Gene mutations linked to worse leukemia outcomes in Hispanic and Latino children
A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine researchers. They said a novel therapeutic drug combination as well as testing for these mutations may help address the disparity.
Hispanic and Latino children are between 1.2 and 1.75 times more likely to develop B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, than non-Hispanic and Latino children. They also have a 40% higher death rate than their counterparts after correcting for socioeconomic factors. Dr. Sinisa Dovat, a researcher and pediatric oncologist at Penn State Children’s Hospital and Penn State Cancer Institute, partnered with Dr. Gordana Raca of Children’s Hospital Los Angeles and Kimberly J. Payne of Loma Linda University to understand the biol ....

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