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Air pollution linked to high blood pressure in children; other studies address air quality and heart


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American Heart Association
Research Highlights:
A meta-analysis of 14 air pollution studies from around the world found that exposure to high levels of air pollutants during childhood increases the likelihood of high blood pressure in children and adolescents, and the risk of hypertension later in life.
A special publication on air pollution features several studies focused on the relationship between ambient air pollution with cardiovascular risk factors such as hypertension.
Other studies cover exposure to diesel exhaust, ambient air pollution and particulate matter and how it affects blood pressure, heart failure admissions and risk of stroke and heart attack. ....

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Gene mutations linked to worse leukemia outcomes in Hispanic and Latino children


Gene mutations linked to worse leukemia outcomes in Hispanic and Latino children
A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine researchers. They said a novel therapeutic drug combination as well as testing for these mutations may help address the disparity.
Hispanic and Latino children are between 1.2 and 1.75 times more likely to develop B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, than non-Hispanic and Latino children. They also have a 40% higher death rate than their counterparts after correcting for socioeconomic factors. Dr. Sinisa Dovat, a researcher and pediatric oncologist at Penn State Children’s Hospital and Penn State Cancer Institute, partnered with Dr. Gordana Raca of Children’s Hospital Los Angeles and Kimberly J. Payne of Loma Linda University to understand the biol ....

Feng Yue , Yali Ding , Mark Reeves , Shriya Kane , Sinisa Dovat , Zissis Chroneos , Daniel Bogush , Joseph Schramm , Elanora Dovat , Los Angeles , Mary Mcgrath , Kimberlyj Payne , Hisham Abdel Azim , Dhimant Desai , Mario Soliman , Yiping Yang , Vladimir Spiegelman , Arati Sharma , Pavan Kumar Dhanyamraju , Arthur Berg , Jonathon Payne , Soumya Iyer , Gordana Raca , Deepa Bhojwani , Chandrika Gowda , Raghavendra Gowda ,

Gene mutations linked to worse outcomes from leukemia in Hispanic and Latino children


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A combination of genetic mutations may explain the higher incidence of and poorer outcomes from pediatric leukemia in Hispanic and Latino children, according to Penn State College of Medicine researchers. They said a novel therapeutic drug combination - as well as testing for these mutations - may help address the disparity.
Hispanic and Latino children are between 1.2 and 1.75 times more likely to develop B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, than non-Hispanic and Latino children. They also have a 40% higher death rate than their counterparts after correcting for socioeconomic factors. Dr. Sinisa Dovat, a researcher and pediatric oncologist at Penn State Children s Hospital and Penn State Cancer Institute, partnered with Dr. Gordana Raca of Children s Hospital Los Angeles and Kimberly J. Payne of Loma Linda University to understand the biology behind this health disparity after prior research suggested that there may be an ....

Feng Yue , Yali Ding , Mark Reeves , Shriya Kane , Sinisa Dovat , Zissis Chroneos , Daniel Bogush , Joseph Schramm , Elanora Dovat , Los Angeles , Mary Mcgrath , Kimberlyj Payne , Hisham Abdel Azim , Dhimant Desai , Mario Soliman , Yiping Yang , Vladimir Spiegelman , Arati Sharma , Pavan Kumar Dhanyamraju , Arthur Berg , Jonathon Payne , Soumya Iyer , Gordana Raca , Deepa Bhojwani , Chandrika Gowda , Raghavendra Gowda ,