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Lung chip model offers new insights into how radiation damages the lungs

The lung is one of the tissues most sensitive to radiation in the human body. People exposed to high radiation doses following nuclear incidents develop radiation-induced lung injury (RILI), which affects the function of many cell types in the lung, causing acute and sustained inflammation, and in the longer term, the thickening and scarring of lung tissue known as fibrosis. ....

United States , Emilia Javorsky , Lily Ramsey , Robert Mannix , Sean Hall , Amanda Jiang , Donald Ingber , Queeny Dasgupta , Amy Wen , Harvard Johna Paulson School Of Engineering , Nature Communications , Network Model For Causality , Wyss Institute , Drug Administration , Wyss Institute At Harvard University , Biologically Inspired Engineering , Harvard University , Boston Children , Wyss Founding Director Donald Ingber , Lung Alveolus Chip , Lung Chip , Organ Chip , Wyss Founding , Judah Folkman Professor , Vascular Biology , Harvard Medical School ,

New microneedles could monitor melanoma therapy response

Patients with melanoma, the most concerning form of skin cancer in which pigment-producing cells start to grow out of control, can benefit from existing immunotherapies, but by far not all of them do. ....

United States , Haim Azhari , Michael Lewandowski , Donald Ingber , Alexander Cryer , Pere Dosta , Megan Craig , Michelle Dion , Rushdy Ahmad , David Walt , Natalie Artzi , Mariana Alonso , Daniel Dahis , Research Scientist , Harvard Johna Paulson School Of Engineering , Principal Research Scientist , Professor Of Medicine At Harvard Medical School , Technion Integrated Cancer Center , Wyss Institute , Weizmann Institute Of Science Women Development Award , Binational Science Fund , Howard Hughes Medical Institute , Professor At Technion Israel Institute Of Technology , Wyss Institute Diagnostic Accelerator Dx , Wyss Institute At Harvard University , Institute For Medical Engineering ,

Implantable Device Adheres to Muscle, Treats Atrophy |

Scientists at the Wyss Institute for Biologically Inspired Engineering at Harvard have developed a mechanically active gel-elastomer-nitinol tissue ....

Dave Mooney , David Mooney , Donald Ingber , Harvard Wyss Institute , Wyss Institute , Biologically Inspired Engineering , Wyss Founding ,

Light-Seq technology for barcoding and deep-sequencing selected cell populations in tissues

Under the microscope, researchers often observe different cell types organizing themselves in peculiar patterns within tissues, or sometimes a rare cell type that stands out by occupying a unique position, exhibiting an unusual shape, or expressing a specific biomarker molecule. ....

United States , Baden Wüberg , Constance Cepko , Ninning Liu , Donald Ingber , Sinem Saka , Jocelyn Josie Kishi , Emily Henderson , Wyss Institute , Wyss Institute Molecular Robotics Initiative , Wyss Technology Development Fellow On Yin , European Molecular Biology Laboratory In Heidelberg , Group Leader , Harvard Johna Paulson School Of Engineering , Blavatnik Institute , Biologically Inspired Engineering , Harvard University , Nature Methods , Peng Yin , Core Faculty , Systems Biology , Harvard Medical School , Gemma West , Wyss Technology Development Fellow , Postdoctoral Fellow , Genomics Industry Focus ,