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Bill Gates, Climate Warrior – and Super Emitter

Bill Gates, Climate Warrior – and Super Emitter
Details
Bill Gates has a new book out:
How to Avoid a Climate Disaster. But some people are less than amused at having to take lessons on the climate crisis from a billionaire who, in the words of the ETC Group, “made a fortune skirting government regulations with monopolistic practices, and holds a significant financial stake in the continued expansion of the fossil fuel industry.”

The following article by Tim Schwab makes clear just how extensive those fossil fuel investments are and how much they are at odds with Bill Gates’ claims. But at the same time as holding significant financial interests in fossil fuel extraction and fossil fuel dependent industries, quite apart from having a massive personal carbon footprint, Gates is also embracing large-scale planetary interventions via risky geoengineering. ....

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New mouse model of SARS-CoV-2 infection reflects features of human infection

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition. ....

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Nanobodies protect against SARS-CoV-2 variants in animal model

Nanobodies protect against SARS-CoV-2 variants in animal model
As of today, the novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than 108 million individuals and claimed the lives of nearly 2.7 million globally. This past year management of the COVID-19 pandemic solely relied on non-pharmaceutical interventions such as school closures, physical distancing, shielding of those at heightened risk, and self-isolation of symptomatic cases.
Currently, prophylactic vaccines - developed at an unprecedented pace are being administered across the globe. However, many viral variants are emerging, threatening the success of the on-going efforts. Despite the adopted mitigation strategies, the COVID-19 pandemic requires multiple countermeasures. ....

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Glyphosate and Roundup disturb gut microbiome and blood biochemistry at doses that regulators claim to be safe

Glyphosate and Roundup disturb gut microbiome and blood biochemistry at doses that regulators claim to be safe
Details
New study reveals evidence for potential cancer-causing damage. Report: Claire Robinson
Glyphosate and the glyphosate-based herbicide Roundup disrupt the gut microbiome by the same mechanism by which the chemical acts as a weedkiller, and these effects happen even at low doses that regulators claim to be safe, a newly published study has found.[1]
The new study was conducted by an international team of scientists based in London, France, Italy, and the Netherlands, led by Dr Michael Antoniou of King’s College London. It is published today in the journal Environmental Health Perspectives. ....

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George Mason researchers investigating COVID-19 therapies

George Mason researchers investigating COVID-19 therapies
Yuntao Wu, Professor, Molecular and Microbiology, and Ramin Hakami, Associate Professor, School of Systems Biology, are conducting studies of COVID-19 therapies.
Recent work from several independent groups has demonstrated that K18-hACE2 transgenic mice serve as an appropriate animal model for studying COVID-19.
Published research has shown that ACE2 is the human cell entry receptor for both SARS and SARS-CoV-2. Research has also shown that K18-hACE2 mice can be used to establish symptomatic SARS-CoV-2 infection that recapitulates many of the COVID-19 findings in human patients, either by infection through the intranasal (IN) route or by intraperitoneal (IP) injection of the virus. Thus, the K18-hACE2 model of SARS-CoV-2 infection recapitulates many features of severe COVID-19 infection in humans and can be used as an in vivo model for testing vaccines and antivirals. ....

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