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Well said! Naugatuck resident wins top prize in Toastmasters speaking contest

WATERBURY Naugatuck resident Stephen Burgess took the top prize at recent public speaking contest put on locally by Toastmasters International, which this year is celebrating 100 years as an organization that provides a platform for individuals to improve their communication, public speaking and ....

Stephen Burgess , Toastmasters International , Premium Content ,

Research Links Circulating Proteins to Pregnancy Hypertension Disorders

Research Links Circulating Proteins to Pregnancy Hypertension Disorders
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United States , Buu Truong , Whitney Hornsby , Maddalena Ardissino , Stephen Burgess , Malissaj Wood , Kathrynj Gray , Mi Jemma Cho , Pradeep Natarajan , Michaelc Honigberg , Tajmara Antoine , Jasond Roh , Amya Sarma , Qi Yan , Zhi Yu , Jamesl Januzzi Jr , Kim Lannery , Tetsushi Nakao , Rohan Bhukar , Colleenm Harrington , Emilys Lau , Darina Postupaka , Nanditas Scott , Adams Butterworth , American Heart Association , Broad Institute ,

MGH study identifies key proteins linked to pregnancy hypertension disorders

Preeclampsia and other hypertensive disorders of pregnancy-;which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy-;carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited. ....

United States , Mi Jemma Cho , Darina Postupaka , Jamesl Januzzi Jr , Jasond Roh , Tajmara Antoine , Adams Butterworth , Stephen Burgess , Malissaj Wood , Qi Yan , Pradeep Natarajan , Maddalena Ardissino , Whitney Hornsby , Michaelc Honigberg , Emilys Lau , Zhi Yu , Colleenm Harrington , Buu Truong , Amya Sarma , Kathrynj Gray , Kim Lannery , Rohan Bhukar , Tetsushi Nakao , Nanditas Scott , Medicine At Harvard Medical School , American Heart Association ,

A drug target for erectile dysfunction to help improve fertility, sexual activity, and wellbeing: mendelian randomisation study

Objective To investigate the association of genetically proxied (using a surrogate biomarker) inhibition of phosphodiesterase 5 (PDE5), an established drug target for erectile dysfunction, with fertility, sexual behaviour, and subjective wellbeing.

Design Two sample cis-mendelian randomisation study.

Setting Summary data on genetic associations obtained from the International Consortium for Blood Pressure and UK Biobank.

Participants Individuals of European ancestry from the International Consortium for Blood Pressure (n=757 601) for estimating PDE5 inhibition (using the surrogate biomarker of diastolic blood pressure reduction), and UK Biobank (n=211 840) for estimating the fertility, sexual behaviour, and subjective wellbeing outcomes in male participants.

Intervention Genetically proxied PDE5 inhibition.

Main outcome measures Number of children fathered, number of sexual partners, probability of never having had sexual intercourse, and subjecti ....

United Kingdom , City Of , Dipender Gill , Benjamin Woolf , James Yarmolinsky , Skanda Rajasundaram , Stephen Burgess , Care Research Cambridge Biomedical Centre , Centre Research Ethics Committee , National Institute For Health , Research Council South West Doctoral Training Partnership , Research Council , Regional Development Agency , Novo Nordisk Foundation , Computing Research Centre , British Heart Foundation , Department Of Health , Cancer Research United Kingdom , International Consortium For Blood Pressure , Innovation Medical Research Council , Doctoral Training Partnership , United Kingdom Research , Research Council Integrated Epidemiology Unit Open , University Of Bristol , International Consortium , Blood Pressure ,