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Medical Research Council responds to long-Covid criticism

The Medical Research Council (MRC) in Swindon has been the target of criticism from long Covid campaigners, who put up a large billboard near the…

A drug target for erectile dysfunction to help improve fertility, sexual activity, and wellbeing: mendelian randomisation study

Objective To investigate the association of genetically proxied (using a surrogate biomarker) inhibition of phosphodiesterase 5 (PDE5), an established drug target for erectile dysfunction, with fertility, sexual behaviour, and subjective wellbeing. Design Two sample cis-mendelian randomisation study. Setting Summary data on genetic associations obtained from the International Consortium for Blood Pressure and UK Biobank. Participants Individuals of European ancestry from the International Consortium for Blood Pressure (n=757 601) for estimating PDE5 inhibition (using the surrogate biomarker of diastolic blood pressure reduction), and UK Biobank (n=211 840) for estimating the fertility, sexual behaviour, and subjective wellbeing outcomes in male participants. Intervention Genetically proxied PDE5 inhibition. Main outcome measures Number of children fathered, number of sexual partners, probability of never having had sexual intercourse, and subjective wellbeing. Results Genetic

Cannabis High Sparks Cognitive Addiction Mechanism

Athersys, Inc.: Grant Awarded to Newcastle University to Research Athersys' MultiStem in Machine Perfusion Prior to Kidney Transplantation

Grant Awarded to Newcastle University to Research Athersys' MultiStem® in Machine Perfusion Prior to Kidney Transplantation