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Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC). ....

Thomas Marron , Barbarab Maier , Brians Kim , Oakleyc Olson , Samarth Hegde , Jill Odonnell Tormey , Briand Brown , Florent Ginhoux , Mark Buckup , Kensuke Miyake , Pauline Hamon , Deborahb Doroshow , Rajwanth Veluswamy , Meriem Belabed , Miriam Merad , Jessica Le Berichel , Seunghee Kim Schulze , Emmanuelle Passegu , Amandam Reid , Erika Nemeth , Vladimir Roudko , Fredr Hirsch , Igor Figueiredo , Nicole Hall , Sacha Gnjatic , Jorgee Gomez ,

A type of allergy medicine might help treat l

<p style="text-align:justify">Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of <em>non-small cell lung cancer (</em>NSCLC)<em>. </em> And in an early parallel study in humans, combining immunotherapy with dupilumab<em>—</em>an <a href="https://www.frontiersin.org/articles/10.3389/fimmu.2018.00888/full" target=" blank">Interleukin-4</a> (IL-4) receptor-blocking antibody widely used for treating allergies and asthma<em>—</em>boosted patients' immune systems, with one out of the six experiencing significant tumor reduction.  The findings were described in the December 6 issue of<em> Nature.</em></p>
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New York , United States , Columbia University , New Providence , East Harlem , Nicole Hall , Jill Odonnell Tormey , Miriam Merad , Pauline Hamon , Nicholas Venturini , Zhaoyuan Liu , Fredr Hirsch , Jessica Le Berichel , Thomasu Marron , Rajwanth Veluswamy , Igor Figueiredo , Kensuke Miyake , Brians Kim , Florent Ginhoux , Theodore Chin , Sacha Gnjatic , Jorgee Gomez , Seunghee Kim Schulze , Mark Buckup , Briand Brown , Samarth Hegde ,

'We had barely got to the beach when there come the Germans' – Islander (99) tells story of Occupation escape bid for first time

AN Islander who is soon to turn 100 has shared the never-before-told story of his attempt to steal a boat and join the D-Day landings during the Occupation. Born on 12 May 1923 in Brighton Road, Richard Ahier is due to celebrate his centenary three d. ....

United States , United Kingdom , Pauline Hamon , Richard Ahier , Brighton Road , Allied Forces , Langley Avenue , Jersey Heritage , Newgate Street , Attorney General , Liberation Day , Enniskillen Dragoon Guards , Korean War , Red Barrel ,

Society for Immunotherapy of Cancer Forward Fund Announces Recipients of 2021 Postdoctoral Cancer Immunotherapy Fellowships and Awards

Society for Immunotherapy of Cancer Forward Fund Announces Recipients of 2021 Postdoctoral Cancer Immunotherapy Fellowships and Awards
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United States , San Diego , Patrick Hwu , Karlo Perica , Laura Donovan , Nanostring Technologie Geomx , Pauline Hamon , Biagio Ricciuti , Nicholas Tschernia , Benjamin Goldenson , Belen Torres , University College London , University Of California , National Cancer Institute , Astrazeneca Pharmaceuticals , University Of North Carolina At Chapel Hill , Bristol Myers Squibb , Dana Farber Cancer Institute , Forward Fund , Nektar Therapeutics , Society For Immunotherapy Of Cancer , National Institutes Of Health , Waltere Washington Convention Center , Forward Fund Fellowships , Koch Institute For Integrative Cancer Research , Icahn School Of Medicine At Mount Sinai ,