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Blocking an allergy pathway unleashes antitumor immunity in mouse models of non-small cell lung cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of non-small cell lung cancer (NSCLC). ....

Thomas Marron , Barbarab Maier , Brians Kim , Oakleyc Olson , Samarth Hegde , Jill Odonnell Tormey , Briand Brown , Florent Ginhoux , Mark Buckup , Kensuke Miyake , Pauline Hamon , Deborahb Doroshow , Rajwanth Veluswamy , Meriem Belabed , Miriam Merad , Jessica Le Berichel , Seunghee Kim Schulze , Emmanuelle Passegu , Amandam Reid , Erika Nemeth , Vladimir Roudko , Fredr Hirsch , Igor Figueiredo , Nicole Hall , Sacha Gnjatic , Jorgee Gomez ,

A type of allergy medicine might help treat l

<p style="text-align:justify">Researchers at the Icahn School of Medicine at Mount Sinai have identified an allergy pathway that, when blocked, unleashes antitumor immunity in mouse models of <em>non-small cell lung cancer (</em>NSCLC)<em>. </em> And in an early parallel study in humans, combining immunotherapy with dupilumab<em>—</em>an <a href="https://www.frontiersin.org/articles/10.3389/fimmu.2018.00888/full" target=" blank">Interleukin-4</a> (IL-4) receptor-blocking antibody widely used for treating allergies and asthma<em>—</em>boosted patients' immune systems, with one out of the six experiencing significant tumor reduction.  The findings were described in the December 6 issue of<em> Nature.</em></p>
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New York , United States , Columbia University , New Providence , East Harlem , Nicole Hall , Jill Odonnell Tormey , Miriam Merad , Pauline Hamon , Nicholas Venturini , Zhaoyuan Liu , Fredr Hirsch , Jessica Le Berichel , Thomasu Marron , Rajwanth Veluswamy , Igor Figueiredo , Kensuke Miyake , Brians Kim , Florent Ginhoux , Theodore Chin , Sacha Gnjatic , Jorgee Gomez , Seunghee Kim Schulze , Mark Buckup , Briand Brown , Samarth Hegde ,

13 myths about lung cancer

In this feature, we address 13 common myths and misconceptions regarding lung cancer. Among other topics, we cover smoking, pollution, and antioxidants. ....

United States , New York , Fredr Hirsch , Joe Lowe , Diego Sabogal , Centers For Disease , Icahn School Of Medicine At Mount Sinai , National Institute On , Disease Control , Thoracic Oncology , Mount Sinai , Tisch Cancer Institute , Louis Price Professor , Medical Oncology , Icahn School , Medical News Today ,

Medical Myths: All about lung cancer

Medical Myths: All about lung cancer ....

United States , New York , Fredr Hirsch , Joe Lowe , Centers For Disease , Icahn School Of Medicine At Mount Sinai , Medical Myths , Disease Control , Trusted Source , Thoracic Oncology , Mount Sinai , Tisch Cancer Institute , Louis Price Professor , Medical Oncology , Icahn School , Medical News Today ,

Spontaneous Cancer Regression Extremely Rare

There is virtually no chance of complete regression and only a 1% chance of any response for patients with advanced solid tumors who receive placebo in cancer drug trials. ....

New York , United States , Fredr Hirsch , Bishal Gyawali , Bhavana Pothuri , American Society Of Clinical Oncology , Queen University , Tisch Cancer Institute At Mount Sinai , Langone Perlmutter Cancer Center , Perlmutter Cancer Center , New York City , Medscape Medical , Tisch Cancer Institute , Mount Sinai , American Society , Clinical Oncology , Alignant Neoplasia , Biologic Therapy , Prostate Carcinoma , Alignant Prostate Neoplasm , Prostate Cancer , Ancer Prostate , Alternative Medicine Complementary , Alternative Treatment , Edicine Alternative Complementary ,