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IFNγ identified as crucial for reducing pulmonary viral loads in COVID-19, new research shows

The role of type-2 interferon (IFNγ) in antiviral immunity. ....

United States , Princejoy Shutterstock , Nature Communications , Bacillus Calmette Gu , Coronavirus Disease Covid 19 , Covid 19 , Ngiotensin Converting Enzyme 2 , Ars Cov 2 , Evere Acute Respiratory , Evere Acute Respiratory Syndrome ,

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third-generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm. ....

San Diego , United States , New Zealand , Peter Lai , Robert Weinkove , Hunan Zhaotai Medical Group , Malaghan Institute Clinical , Guangzhou Institute Of Biomedicine , Wellington Zhaotai Therapies , Malaghan Institute Of Medical Research , Wellington Zhaotai Therapies Limited , Malaghan Institute , American Society Of Hematology , Medical Research , American Society , Annual Meeting , Malaghan Institute Clinical Director , Principal Investigator Dr Robert , Guangzhou Institute , Hunan Zhaotai Medical , Wellington Zhaotai Therapies Limited Executive , Professor Carl June , Clinical Trial , Cart Cell , Chimeric Antigen Receptor , Medical Research ,

IU researchers uncover novel mechanism of pathogen entry into cells

Similar to a burglar breaking a window to get into a house, Indiana University researchers have discovered a previously unknown process by which pathogens enter a cell with physical force, breaching the body's immune defenses that prevent infection. ....

Thomask Gaetjens , Yan Yu , Zihan Zhang , Yanqi Yu , Stevenm Abel , Qiong Zhou , National Institutes Of Health , National Science Foundation , University Of Tennessee , College Of Arts , Proceedings Of The National Academy Sciences , Science Department Of Chemistry , Indiana University , National Academy , Science Department , National Institutes , National Science , Infectious Diseases ,

Rare bacterial strain yields groundbreaking compounds to combat hepatitis B

Scientists have discovered new antiviral compounds from a rare bacterial strain, offering a novel approach to target hepatitis B virus. These compounds work by altering membrane permeability in infected cells, leading to the release of immature viral particles, a mechanism distinct from current HBV treatments. ....

Sanchari Sinha Dutta , Institute Of Microbial Chemistry , Microbial Chemistry , Hepatitis B , Hepatitisb Virus , Hepatocellular Carcinoma ,

Breakthrough in HIV treatment: NMN shows promise in reducing CD4+ T cell activation

The impact of nicotinamide mononucleotide (NMN) on Clusters of differentiation 4+ (CD4+ ) Thymus cells (T cells) viz. ....

Rapeepat Pornsipak Shutterstock , Human Embryonic Kidney , Linked Immunosorbent Assay , Human Leukocyte Antigen , Cell Line , Cell Metabolism , Hiv 1 , Vitamin D ,