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New Study Sheds Light on the Cause of Severe Inflammatory Bowel Disease

Scientists at Cedars-Sinai have identified a genetic variant that is associated with perianal Crohn's disease. Investigators at Cedars-Sinai have discovered a genetic variant that elevates an individual's likelihood of experiencing perianal Crohn's disease, which is considered to be the most severe ....

United States , Lisas Thomas , Stevenr Brant , Hussein Hamade , Erica Vasiliauskas , Johnd Rioux , Shervin Rabizadeh , Gily Melmed , Davida Ziring , Williama Faubion , Nirupaman Bonthala , Lisaz Greer , Dalin Li , Gregoryj Botwin , Alkaa Potdar , Phillip Fleshner , L Philip Schumm , Marks Silverberg , Michelle Khrom , Ramachandran Murali , Richardh Duerr , Roberts Sandler , Judyh Cho , Emebet Mengesha , Carolj Landers , Ramnikj Xavier ,

Newly discovered genetic variant increases risk of developing perianal Crohn's disease

Cedars-Sinai investigators have identified a genetic variant that increases people's risk of developing perianal Crohn's disease, the most debilitating manifestation of Crohn's disease. ....

United States , Marzieh Akhlaghpour , Talin Haritunians , Hussein Hamade , Gily Melmed , Gregoryj Botwin , Alkaa Potdar , Gaurav Syal , Andreaj Wolf , Ramachandran Murali , Michelle Khrom , Perianal Crohn , Emily Henderson , Stephan Targan , Kathrin Michelsen , Nirupaman Bonthala , Shishir Dube , Emebet Mengesha , Carolj Landers , Lisas Thomas , Lisaz Greer , Shaohong Yang , Erica Vasiliauskas , Dermot Mcgovern , Dalin Li , Immunobiology Research Institute ,

Insight into Cause of Severe Inflammatory Bowel Disease: Study

Insight into Cause of Severe Inflammatory Bowel Disease: Study
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United States , Dermot Mcgovern , Gaurav Syal , Erica Vasiliauskas , Talin Haritunians , Hussein Hamade , Lisaz Greer , Michelle Khrom , Emebet Mengesha , Alkaa Potdar , Marzieh Akhlaghpour , Nirupaman Bonthala , Kathrin Michelsen , Gregoryj Botwin , Lisas Thomas , Stephan Targan , Dalin Li , Ramachandran Murali , Perianal Crohn , Shaohong Yang , Andreaj Wolf , Gily Melmed , Carolj Landers , Shishir Dube , National Institutes Of Health , Biomedical Sciences At Cedars ,

Study gives insight into cause of severe inflammatory bowel disease

Study gives insight into cause of severe inflammatory bowel disease
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United States , Erica Vasiliauskas , Stephan Targan , Michelle Khrom , Shishir Dube , Gregoryj Botwin , Shaohong Yang , Carolj Landers , Andreaj Wolf , Gaurav Syal , Hussein Hamade , Talin Haritunians , Ramachandran Murali , Marzieh Akhlaghpour , Dermot Mcgovern , Perianal Crohn , Alkaa Potdar , Emebet Mengesha , Dalin Li , Lisas Thomas , Kathrin Michelsen , Gily Melmed , Lisaz Greer , Nirupaman Bonthala , Sinaif Widjaja Foundation Inflammatory Bowel , Translational Research ,

Study gives insight into cause of severe infl

Cedars-Sinai investigators have identified a genetic variant that increases people’s risk of developing perianal Crohn’s disease, the most debilitating manifestation of Crohn’s disease. The variant generates changes to DNA that lead to a loss of protein function, which in turn, alters how the body recognizes and handles bacteria, making it less effective at fighting infections. ....

United States , Gregoryj Botwin , Michelle Khrom , Dalin Li , Gaurav Syal , Ramachandran Murali , Lisaz Greer , Perianal Crohn , Alkaa Potdar , Kathrin Michelsen , Emebet Mengesha , Shishir Dube , Andreaj Wolf , Hussein Hamade , Lisas Thomas , Gily Melmed , Erica Vasiliauskas , Carolj Landers , Talin Haritunians , Shaohong Yang , Dermot Mcgovern , Stephan Targan , Marzieh Akhlaghpour , Nirupaman Bonthala , Translational Research , Biomedical Sciences At Cedars ,