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Harvard and MIT Scientists Discover Cholesterol-Busting Microbes in the Gut

Research identifies multiple types of bacteria that metabolize cholesterol in individuals with reduced cholesterol levels. Alterations in the gut microbiome are associated with a range of diseases, such as type 2 diabetes, obesity, and inflammatory bowel disease. Now, a team of researchers at th ....

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New Study Sheds Light on the Cause of Severe Inflammatory Bowel Disease

Scientists at Cedars-Sinai have identified a genetic variant that is associated with perianal Crohn's disease. Investigators at Cedars-Sinai have discovered a genetic variant that elevates an individual's likelihood of experiencing perianal Crohn's disease, which is considered to be the most severe ....

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New study sheds light on cause of severe inflammatory bowel disease

  Perianal Crohn’s disease is a type of inflammatory bowel disease that affects the area around the anus. It can cause symptoms such as pain, itching and discharge, as well as more serious complications such as abscesses and fistulas. Scientists at Cedars-Sinai have identified a genetic mutation associated with perianal Crohn’s disease. Investigator Cedars Sinai […] ....

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Giving cells an appetite for viruses


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IMAGE: A UT Southwestern study identified a gene used in the cellular recycling process called autophagy that rids cells of viruses. The above illustration breaks down the steps involved in this.
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Credit: UT Southwestern Medical Center
DALLAS - Dec. 16, 2020 - A team led by UT Southwestern researchers has identified a key gene necessary for cells to consume and destroy viruses. The findings, reported online today in
Nature, could lead to ways to manipulate this process to improve the immune system s ability to combat viral infections, such as those fueling the ongoing COVID-19 pandemic.
Scientists have long known that cells use a process called autophagy to rid themselves of unwanted material. Autophagy, which translates as self-eating, involves isolating cellular garbage in double-layered vesicles called autophagosomes, which are then fused with single-layered vesicles known as lysosomes to degrade the materials inside and re ....

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