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Cellular immunotherapy: a new approach against cancer

Aggressive lymphomas – colloquially known as cancers of the lymph nodes – are the fifth most common cause of death from cancer in Germany. Can their treatment be improved via cellular immunotherapy? ....

Nordrhein Westfalen , West German , Christian Reinhardt , University Of Cologne , German Cancer Centre , University Duisburg , Department Of Hematology , German Center , Department Of Dermatology , University Hospital Essen United Kingdom , Max Planck Institute For Molecular Physiology , Department Of Internal Medicine , Stem Cell , Internal Medicine , University Hospital Essen , United Kingdom Essen , West German Cancer Centre , Max Planck Institute , Molecular Physiology , Stem Cell Transplantation ,

Scientists to present new findings on protein biochemistry, glycobiology at Life Science Symposium 2021

Scientists to present new findings on protein biochemistry, glycobiology at Life Science Symposium 2021
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Baden Wüberg , Thomas Dyer Seeley , Mathias Heikenw , Emily Henderson , Ludger Johannes , Technische Universitaet Braunschweig , Miguel Vences , Christian Fankhauser , Melina Schuh , Asifa Akhtar , Stefan Raunser , Institut Curie , Rohini Kuner , Max Planck Institute For Developmental Biology , Cornell University United States , University Of Lausanne Switzerland , German Cancer Research Center , Max Planck Institute For Molecular Physiology , University Of Heidelberg Germany , Life Sciences , Max Planck Institute Of Immunobiology , Max Planck Institute For Biophysical Chemistry , German National Academy , Sciences Leopoldina , Science Symposium , Class Symposia ,

Research team investigates causes of tuberous sclerosis

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IMAGE: Dr. Katharina Fitzian, Prof. Dr. Daniel Kümmel, Dr. Andrea Oeckinghaus and Anne Brückner (from left) in their laboratories. The collage in the middle illustrates the structure of the TSC1 membrane.
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Credit: Kümmel team/Oeckinghaus team
Tuberous Sclerosis Complex (TSC) affects between one and two of every 10,000 new-born babies. This genetic disease leads to the formation of benign tumours which can massively impair the proper functioning of vital organs such as the kidneys, the liver and the brain. The disease affects different patients to varying degrees and is triggered by mutations in one of two genes, the TSC1 or TSC2 gene. An interdisciplinary team of researchers led by biochemists Prof. Daniel Kümmel and Dr. Andrea Oeckinghaus from the University of Münster (Germany) examined the tumour suppressor protein TSC1 and, for the first time, gained insights into its hitherto unclear functions. The team identified a new mecha ....

Stephan Raunser , Constantinos Demetriades , Andrea Oeckinghaus , University Hospital , Max Planck Institute For Molecular Physiology , Institute Of Molecular Tumour Biology , University Faculty Of Chemistry , Institute Of Biochemistry , University Faculty Of Medicine , Tuberous Sclerosis Complex , Molecular Cell , University Faculty , Molecular Tumour Biology , Max Planck Institute , Molecular Physiology , பல்கலைக்கழகம் மருத்துவமனை , நிறுவனம் ஆஃப் உயிர் வேதியியல் , பல்கலைக்கழகம் ஆசிரிய ஆஃப் மருந்து , கிழங்கு ஸ்க்லரோசிஸ் சிக்கலான , மூலக்கூறு செல் , பல்கலைக்கழகம் ஆசிரிய , மூலக்கூறு உடலியல் ,