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Research reveals clever dosage control mechanism of biallelic genes

Research reveals clever dosage control mechanism of biallelic genes
phys.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from phys.org Daily Mail and Mail on Sunday newspapers.

Asifa Akhtar , Steffen Dietzel Wikipedia , Meike Wiese , Yidan Sun , Max Planck Institute Of Immunobiology , Max Planck Institute ,

Revisiting gene dosage

<p><strong>Researchers have uncovered a mechanism that safeguards the biallelic expression of haploinsufficient genes, shedding light on the importance of having two copies of each chromosome. A study by the lab of Asifa Akhtar identified the epigenetic regulator MSL2 an &ldquo;anti-monoallelic&rdquo; factor that maintains biallelic gene dosage. This discovery not only reveals a communication system between parental alleles but also points to potential therapeutic strategies for diseases associated with haploinsufficient genes.</strong></p>
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Meike Wiese , Asifa Akhtar , Yidan Sun , Method Of Research , Max Planck Institute Of Immunobiology , Max Planck Institute ,

Clever dosage control mechanism of biallelic genes

Clever dosage control mechanism of biallelic genes
sciencedaily.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from sciencedaily.com Daily Mail and Mail on Sunday newspapers.

Meike Wiese , Asifa Akhtar , Yidan Sun , Max Planck Institute Of Immunobiology , Max Planck Institute ,