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Cellular immunotherapy: a new approach against cancer

Aggressive lymphomas – colloquially known as cancers of the lymph nodes – are the fifth most common cause of death from cancer in Germany. Can their treatment be improved via cellular immunotherapy? ....

Nordrhein Westfalen , West German , Christian Reinhardt , University Of Cologne , German Cancer Centre , University Duisburg , Department Of Hematology , German Center , Department Of Dermatology , University Hospital Essen United Kingdom , Max Planck Institute For Molecular Physiology , Department Of Internal Medicine , Stem Cell , Internal Medicine , University Hospital Essen , United Kingdom Essen , West German Cancer Centre , Max Planck Institute , Molecular Physiology , Stem Cell Transplantation ,

Where Does Ripretinib Fit Into Treatment for GIST?

The relative newcomer to the field, ripretinib, was compared to standard second-line treatment with sunitinib in patients with advanced gastrointestinal stromal tumors. ....

New York , United States , Columbia University , West German , Sebastian Bauer , Gary Schwartz , Daiichi Sankyo , Nanobiotix Incyte , Drug Administration , Boehringer Ingelheim , Deciphera Pharmaceuticals , German Cancer Centre , Clinical Oncology , West German Cancer Centre , Blueprint Medicines , Adcendo Aps , Gastrointestinal Stromal Tumor , Umor Gastrointestinal Stromal , Antineoplastic Drug , Nti Cancer Agents , Biologic Therapy , Antibody Drug Conjugates Adcs , Clinical Research , Clinical Trials , Linical Studies , Healthcare And Medical Technology ,

VRK1: a protein that reduces the survival of patients with neuroblastoma

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Researchers from the Departments of Cell Biology and Medical Physiology at the University of Seville have identified that a high expression of the human protein VRK1 is associated with tumour aggressiveness and low survival among neuroblastoma patients. Aggressive neuroblastoma is one of the most common solid childhood cancers and causes disproportionately high mortality in affected children. Although advances have been made in recent years, the outlook for recovery in children affected by aggressive neuroblastoma remains low and a better understanding of this tumour s biology is needed in order to create new treatments and prognostic tools.
Researchers have characterised the function of VRK1 in neuroblastoma tumour cells and have determined that this protein is essential for tumour cell growth and proliferation. By studying the expression of this protein in tumours, we were able to identify a priori patients where tumour progression is going to be worse, even i ....

Baden Wuberg , Franciscom Vega , Ricardo Pardal , German Cancer Centre , University Of Seville , Department Of Cell Biology , Association Of Family , Institute Of Biomedicine Seville Ibi , Ministry Of Science , Cell Biology , Medical Physiology , Andalusian Regional , Ana Colmenero Repiso , ஜெர்மன் புற்றுநோய் மையம் , பல்கலைக்கழகம் ஆஃப் செவில்லே , துறை ஆஃப் செல் உயிரியல் , சங்கம் ஆஃப் குடும்பம் , அமைச்சகம் ஆஃப் அறிவியல் , செல் உயிரியல் , மருத்துவ உடலியல் , அண்டலூசின் பிராந்திய ,