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Venom s usually the stuff of nightmares. Animals that wield it send instinctive shivers down our spines. But scientists are teasing out useful purposes for these powerful substances that (sometimes incidentally) can cause us so much pain and damage. Recently we ve seen developments from several types of venoms, from bee venom as a cancer treatment to using platypus venom for diabetes.
A team of researchers has developed the next venom-based medical advancement: a fast-acting super glue that stops bleeding in under a minute. While synthetic adhesives can be easier to manipulate, their degradation can potentially be toxic. Meanwhile, natural bioadhesives are more likely to have excellent biocompatibility , explained the authors in their new paper, but limited overall integrity and adhesion. ....
Irritable bowel syndrome endoscopically identifiable from mucosal biofilms eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.
Mar 12 2021 Read 412 Times In a recent study led by MedUni Vienna and the University of Vienna, researchers demonstrated that dimerized (a combination of two identical or different molecules) and therefore significantly larger versions of human neuropeptides oxytocin and vasopressin are still able to activate their receptors without forfeiting too much of their efficacy. Such new constructs provide several opportunities to optimise the efficacy of these neuropeptides for therapeutic application. Oxytocin/vasopressin receptors are typical examples of so-called G protein-coupled receptors – the most successful drug target class, which are being investigated for therapeutic applications in cardiovascular disease, cancer and developmental disorders such as autism. ....
Scientists present new outlook on latest trends in peptide drug discovery and development Currently there are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases such as diabetes, cancer, hormone disorders, HIV infection, and multiple sclerosis. In the recent issue of Nature Reviews Drug Discovery , a team of Austrian and Australian scientists led by medicinal chemist Markus Muttenthaler of the University of Vienna present an outlook on the latest trends in peptide drug discovery and development. ....
There are more than 80 peptide drugs on the global market and about twice as many in clinical development. Due to their beneficial properties, these biomolecules play already an important role in the treatment of diseases. In ....