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New insights on polymicrobial infections in chronic lung diseases

Chronic lung diseases are often accelerated and exacerbated by polymicrobial infections. An international study has identified two types of these so-called dysbioses in cystic fibrosis. They display distinct ecology and are also likely to respond differently to treatment. ....

United States , Johnj Lipuma , Stefanie Widder , Division Of Infection Biology , University Of Michigan Medical School Ann Arbor , Stefanie Widder Department Of Medicine , Meduni Vienna , Michigan Medical School Ann Arbor , Infection Biology ,

Inhibition of epigenetic control enzymes in immune cells as a potential new starting point in cancer immunotherapy

Immunotherapy is one of the pillars in the fight against cancer and aims to enable the body s own immune system to fight a tumor. A recent study now shows that removing certain enzymes that regulate epigenetic processes from the so-called dendritic cells of the immune system influences their development and thus improves anti-tumor immunity. ....

Maria Sibilia , Cancer Research , Cancer Center , Cell Reports , Comprehensive Cancer Center , Meduni Vienna , Vienna General Hospital ,