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USC researchers find genetic variant contribu

<p style="text-align:start">Children of Hispanic/Latino origin are 30-40% more likely to get Acute lymphoblastic leukemia (ALL) than non-Hispanic white children. However, the exact genetic basis and cause of that increased risk are unknown. Now researchers have revealed a key genetic variant contributing towards the increased risk, as well as details about the biological basis of ALL. The research team focused on the <em>IKZF1 </em>gene, known to relate to ALL but never before linked with ethnic risk disparities. Using genetic fine-mapping analysis, they independently analyzed each position along the gene—known as a single nucleotide polymorphism (SNP)—to determine whether having a certain variant increased ALL risk. They found three independent SNPs linked to higher ALL incidence, one of which was present in about 30% of people of Hispanic/Latino origin in the U.S. and less than 1%  of people ....

New York , United States , Dana Farber Cancer Institute , Jun Yang , Stanford University , San Francisco , Soyoung Jeon , Tsz Fung Chan , Catherine Metayer , Soumyaa Mazumder , Xiaomei Ma , Esteban Gonzalez Burchard , Guangze Xia , Steven Gazal , Joseph Wiemels , Vijay Sankaran , Nathan Nakatsuka , Nicholas Mancuso , Elad Ziv , Lara Wahlster , Celeste Eng , Wenjian Yang , Charleston Chiang , Jalen Langie , Linda Kachuri , Fulong Yu ,

Study reveals genetic variant linked to increased risk of leukemia in Hispanic/Latino children

Acute lymphoblastic leukemia (ALL), the most common childhood cancer, disproportionately affects children of Hispanic/Latino origin in the United States. ....

San Francisco , United States , Stanford University , Dana Farber Cancer Institute , Jun Yang , New York , Charleston Chiang , Lara Wahlster , Xiaomei Ma , Nathan Nakatsuka , Jalen Langie , Nicholas Mancuso , Celeste Eng , Tsz Fung Chan , Vijay Sankaran , Catherine Metayer , Steven Gazal , Elad Ziv , Esteban Gonzalez Burchard , Soyoung Jeon , Soumyaa Mazumder , Guangze Xia , Fulong Yu , Linda Kachuri , Wenjian Yang , Joseph Wiemels ,

USC researchers find genetic variant contribu

USC researchers find genetic variant contribu
eurekalert.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from eurekalert.org Daily Mail and Mail on Sunday newspapers.

United States , Jun Yang , Stanford University , San Francisco , Dana Farber Cancer Institute , New York , Vijay Sankaran , Fulong Yu , Catherine Metayer , Joseph Wiemels , Lara Wahlster , Tsz Fung Chan , Linda Kachuri , Nathan Nakatsuka , Nicholas Mancuso , Celeste Eng , Esteban Gonzalez Burchard , Guangze Xia , Xiaomei Ma , Wenjian Yang , Soyoung Jeon , Jalen Langie , Elad Ziv , Charleston Chiang , Steven Gazal , Soumyaa Mazumder ,

Genetically Adjusted PSA Levels Improve Prediction of Prostate Cancer

Genetically Adjusted PSA Levels Improve Prediction of Prostate Cancer
renalandurologynews.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from renalandurologynews.com Daily Mail and Mail on Sunday newspapers.

United States , San Francisco , Linda Kachuri , University Of California , Healthday News ,

Scientists Get Closer to a Better PSA Test

MONDAY, June 5, 2023 (HealthDay News) The most common screening test for prostate cancer so often returns a false positive result that it’s no longer recommended for men older ....

United States , Linda Kachuri , John Witte , American Cancer Society , Healthday News , Stanford Medicine , East Asian , Consumer News ,