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Scientists uncover key to enhancing cancer-killing T cells

T cells are the key immune system component involved in killing cancer. Tumors produce signals that turn off these T cells, partially by forcing them to progressively differentiate (mature) into a hypofunctional state known as exhaustion. ....

Jordy Saravia , Peipei Zhou , Shondra Pruett Miller , Hongbo Chi , Hongling Huang , Nicole Chapman , Jonp Connelly , Xiang Sun , Zhao Shi , Cancer Center Support Grant , National Institutes Of Health , Jude Children Research Hospital , Jude Department Of Immunology , Jude Children , Research Hospital , Jude Department , Sujing Yuan , Seon Ah Lim , National Institutes , T Cell , Bone Marrow , Ancer Immunotherapy , Chimeric Antigen Receptor , Ene Expression , Immune System , Transcription Factors ,

T cells in the brain slow progression of Alzheimer's

Scientists have found that a subset of CD8<sup>+</sup> T cells in the brain lessens the activation of microglia and limits disease pathology in a model of Alzheimer's disease. ....

Jordy Saravia , Hongbo Chi , Wei Su , Jude Children Research Hospital , Jude Children , Research Hospital , Alzheimer Amp 39 S , St Jude Childrens Research Hospital , Nature Immunology , Cd8t Cells , Immune Cells ,

How specific T cells in brain slow progression of Alzheimer's disease: Study | Health

The study states how T cells helps in slowing down Alzheimer’s by interacting with microglia - immunological cells in brain that remove beta-amyloid plaques. | Health ....

United States , Hongbo Chi , Wei Su , Jordy Saravia , Jude Department Of Immunology , Jude Children Research Hospital , Jude Children , Research Hospital , Jude Department , Alzheimer Disease , Alzheimer S , Alzheimers Disease , Slow Progression Of Alzheimers Disease , T Cells In Brain Slow Progression Of Alzheimers Disease ,

Study finds how specific T cells in brain slow progression of Alzheimers disease

Study finds how specific T cells in brain slow progression of Alzheimers disease
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United States , Jordy Saravia , Wei Su , Hongbo Chi , Jude Children Research Hospital , Jude Department Of Immunology , Jude Children , Research Hospital , Jude Department ,

Study finds how specific T cells in brain slow progression of Alzheimer's disease

Study finds how specific T cells in brain slow progression of Alzheimer's disease
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United States , Wei Su , Hongbo Chi , Jordy Saravia , Jude Children Research Hospital , Jude Department Of Immunology , Jude Children , Research Hospital , Jude Department ,