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A new perspective on genomes of archaic humans

Stanford University
A genome by itself is like a recipe without a chef – full of important information, but in need of interpretation. So, even though we have sequenced genomes of our nearest extinct relatives – the Neanderthals and the Denisovans – there remain many unknowns regarding how differences in our genomes actually lead to differences in physical traits.
“When we’re looking at archaic genomes, we don’t have all the layers and marks that we usually have in samples from present-day individuals that help us interpret regulation in the genome, like RNA or cell structure,” said David Gokhman, a postdoctoral fellow in biology at Stanford University. ....

Stanford University , United States , San Francisco , David Gokhman , Dmitri Petrov , Nadav Ahituv , Lana Harshman , Carly Weiss , University Of California , School Of Humanities , Kevin Douglas Professor , University Of California , Stanford University , San Francisco , ஸ்டான்போர்ட் பல்கலைக்கழகம் , ஒன்றுபட்டது மாநிலங்களில் , சான் பிரான்சிஸ்கோ , டேவிட் கோக்மான் , டமீட்ரீ பெட்ரோவ் , பல்கலைக்கழகம் ஆஃப் கலிஃபோர்னியா , பள்ளி ஆஃப் மனிதநேயம் , கெவின் டக்ளஸ் ப்ரொஃபெஸர் ,

New, high-performance artificial muscle technology enables more human-like motion

New, high-performance artificial muscle technology enables more human-like motion
In the field of robotics, researchers are continually looking for the fastest, strongest, most efficient and lowest-cost ways to actuate, or enable, robots to make the movements needed to carry out their intended functions.
The quest for new and better actuation technologies and soft robotics is often based on principles of biomimetics, in which machine components are designed to mimic the movement of human muscles and ideally, to outperform them. Despite the performance of actuators like electric motors and hydraulic pistons, their rigid form limits how they can be deployed. As robots transition to more biological forms and as people ask for more biomimetic prostheses, actuators need to evolve. ....

Diego Higueras Ruiz , Michael Shafer , Heidi Feigenbaum , Emily Henderson , Development Preliminary , Northern Arizona University Department Of Mechanical Engineering , Dynamic Active Systems Laboratory , Northern Arizona University , Mechanical Engineering , Science Robotics , Reactive Systems , Associate Professor , Development Preliminary Studies , மைக்கேல் ஷாபெர் , எமிலி ஹென்டர்சன் , வடக்கு அரிசோனா பல்கலைக்கழகம் , இயந்திர பொறியியல் , அறிவியல் ரோபாட்டிக்ஸ் , செயலில் அமைப்புகள் , இணை ப்ரொஃபெஸர் ,

HSS' doctor performs first total wrist replacement surgery with KinematX implant

HSS’ doctor performs first total wrist replacement surgery with KinematX implant
Sixty-nine-year-old Mark Eisen says he waited seven years for a surgery he hopes will change his life. Last week, he had the first total wrist replacement with KinematX™, a new implant co-designed by Scott Wolfe, MD, chief emeritus of the Hand and Upper Extremity Service at Hospital for Special Surgery (HSS). Dr. Wolfe performed the surgery on April 15.
Severe arthritis in his right wrist caused ongoing pain and prevented Mr. Eisen, who lives in Atlanta, from engaging in activities he enjoys.
He is right-handed, which makes it even more difficult. Seven years ago, he started to investigate treatments and learned about total wrist replacement surgery. But unlike knee and hip replacements, which are common and have excellent outcomes, wrist replacement surgery has not enjoyed the same degree of success. ....

New York , United States , Mark Eisen , Scott Wolfe , Doug Leach , Josephj Trey Crisco , Emily Henderson , Extremity Medical , Innovation Institute , National Institutes Of Health , Drug Administration , Brown University , Warren Alpert Medical School , Upper Extremity Service , Special Surgery , Rhode Island Hospital , Total Wrist Arthoplasty System , National Institutes , Biomechanical Innovation , Medical School , புதியது யார்க் , ஒன்றுபட்டது மாநிலங்களில் , குறி ேசென் , ஸ்காட் ஓநாய் , டக் லீச் , எமிலி ஹென்டர்சன் ,

New research could help solve major challenge in the deployment of COVID-19 vaccines

New research could help solve major challenge in the deployment of COVID-19 vaccines
New research by University of Texas at Dallas scientists could help solve a major challenge in the deployment of certain COVID-19 vaccines worldwide the need for the vaccines to be kept at below-freezing temperatures during transport and storage.
In a study published online April 13 in
Nature Communications, the researchers demonstrate a new, inexpensive technique that generates crystalline exoskeletons around delicate liposomes and other lipid nanoparticles and stabilizes them at room temperature for an extended period up to two months in their proof-of-concept experiments.
The Moderna and Pfizer/BioNTech COVID-19 vaccines use lipid nanoparticles basically spheres of fat molecules to protect and deliver the messenger RNA that generates a vaccine recipient s immune response to the SARS-CoV-2 virus. ....

Rhode Island , United States , Gabriele Meloni , Sameera Abeyrathna , Jeremiah Gassensmith , Emily Henderson , Nisansala Abeyrathna , Nature Communications , University Of Texas At Dallas , School Of Natural Sciences , Us Postal Service , Natural Sciences , Cold Chain , Immune Response , Ars Cov 2 , ரோட் தீவு , ஒன்றுபட்டது மாநிலங்களில் , கேப்ரியல் மெலோனி , எமிலி ஹென்டர்சன் , இயற்கை தகவல்தொடர்புகள் , பல்கலைக்கழகம் ஆஃப் டெக்சாஸ் இல் டல்லாஸ் , பள்ளி ஆஃப் இயற்கை அறிவியல் , எங்களுக்கு போஸ்டல் சேவை , இயற்கை அறிவியல் , பழையது சங்கிலி ,

Modified Nanoparticles Can Stop Osteoarthritis Development

PHILADELPHIA After a team of researchers showed that a certain enzyme's presence in cartilage increased significantly in people with osteoarthritis,. ....

University Of Pennsylvania , United States , Biang Jang , Zhiliang Cheng , Lesan Yan , Ahmad Amirshaghaghi , Yulong Wei , Lijun Luo , Andrew Tsourkas , Penn Medicine Mckay Orthopaedic Research Laboratory , National Institutes Of Health , Ling Qin , Penn Medicine , Mckay Orthopaedic Research Laboratory , National Institutes , Tao Gui , Tianyan You , Penn Medicine , Science Advances , Clinical Trials , பல்கலைக்கழகம் ஆஃப் பென்சில்வேனியா , ஒன்றுபட்டது மாநிலங்களில் , லேசான் யான் , யுளோங் வெய் , தேசிய நிறுவனங்கள் ஆஃப் ஆரோக்கியம் , லிங் குயின் ,