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UC San Diego School of Medicine researchers discovered gene expression patterns associated with pandemic viral infections, providing a map to help define patients immune responses, measure disease severity, predict outcomes and test therapies for current and future pandemics. ....
Despite knowing about decompression sickness - or the bends - for more than a century, researchers are still mystified about how this condition occurs. A new study published by the open access journal Frontiers is the first to explore the genetic changes that occur in humans with the bends. It reveals that genes involved in white blood cell activation and inflammation are upregulated in divers with this condition. The results may pave the way for tests that allow doctors to diagnose decompression sickness more easily. ....
E-Mail A condition that affects the blood, known as idiopathic thrombocytopenic purpura (ITP), may be associated the Oxford-AstraZeneca vaccine in rare cases, research suggests. The very small increased risk of the condition - which is characterised by low platelet counts - is estimated to be 11 per million doses, similar to figures seen in vaccines for flu and MMR. A low number of platelets - blood cells that help prevent blood loss when vessels are damaged - can result in no symptoms or can lead to an increased risk of bleeding or, in some cases, clotting. Researchers say that the increased chance of developing ITP after receiving the vaccine remains smaller than the risk of developing it because of Covid-19 and should not deter the roll out of the vaccine programme. ....
Top: β-lactam antimicrobial agents rupture bacteria by destroying their cell walls. Bottom: The red text in the structural formula represents the β-lactam ring, which is essential for bactericidal action. . view more Credit: Professor Tomohiro Sawa A joint research project based in Kumamoto University, Japan has developed a new, highly sensitive analytical method that can detect degraded β-lactam antibacterial agents used in the treatment of bacterial infections. With this method, researchers found that reactive sulfur species produced by bacteria degrade and inactivate β-lactam antibiotics. Bacteria are different from animal cells in that their outer layer is covered with a rigid structure called a cell wall. β-lactam antimicrobial agents interfere with the processes that form the cell wall. This results in bacteria no longer being able to withstand their own internal pressure so they rupture and die. β-lactam antimicrobial agents are very pote ....
Researchers from York University and the University of British Columbia have found social media use to be one of the factors related to the spread of COVID-19 within dozens of countries during the early stages of the pandemic. The researchers say this finding resembles other examples of social media misinformation ranging from the initial phase of vaccine rollout to the 2021 Capitol riot in the United States. ....