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In all surgery types, subgroups and outcome time points, NSAIDs were equal or superior to codeine for postoperative pain, writes Dr. Matthew Choi, Associate Professor of Surgery, McMaster University, with coauthors. The researchers conducted a systematic review and meta-analysis of 40 high-quality randomized controlled trials (RCTs) involving more than 5100 adults to compare pain levels and safety of medications containing codeine, such as Tylenol #3, with NSAIDs. Patients who took NSAIDs had lower pain scores at 6 and 12 hours after treatment than patients taking codeine. We found that patients randomized to NSAIDs following outpatient surgical procedures reported better pain scores, better global assessment scores, fewer adverse effects and no difference in bleeding events, compared with those receiving codeine, write the authors. ....
E-Mail Early in her career neuroscientist Allyson Mackey began thinking about molars. As a researcher who studies brain development, she wanted to know whether when these teeth arrived might indicate early maturation in children. I ve long been concerned that if kids grow up too fast, their brains will mature too fast and will lose plasticity at an earlier age. Then they ll go into school and have trouble learning at the same rate as their peers, says Mackey, an assistant professor in the Department of Psychology at Penn. Of course, not every kid who experiences stress or [is] low income will show this pattern of accelerated development. ....
Cells/colony motion of oral keratinocytes was non-invasively and quantitatively determined by optical flow algorithm. As per the distinct cell growth kinetics, modified optic flow algorithm was applied with fewer full-screening imaging analyses & cell segmentations, which confirmed the association of proliferative capacity & epithelial regenerative capacity with mean motion speed (MMS). The index of MMS was identified to detect the substandard population, prior to human clinical use, which may be applied to other cell cultures. ....
Dental care professionals are thought to be at enhanced risk of occupational exposure to SARS-CoV-2, but robust data to support this is lacking. The study COVID-19: Seroprevalence and Vaccine Responses in UK Dental Care Professionals, published in the Journal of Dental Research (JDR), provides a longitudinal analysis of antibodies to SARS-CoV-2 spike glycoprotein, including early analysis of the impact of vaccination on the immune response. ....
Credit: Flinders University What keeps consumers hooked on high sugar soft drink? Advertising, of course. But why are some consumers more adept at ignoring these cues than others? A new study from Flinders University, published in Appetite, found participants with an automatic bias towards soft drinks - or difficulty resisting sweet drinks compared to non-sweetened control beverages (e.g., water) - were more responsive to the ads than those without these tendencies. The Australian study compared the ability of 127 university-age students (18-25 year olds) to withstand or succumb to the urge to reach for a soft drink when viewing television advertisements. ....