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Efficacy of psilocybin for treating symptoms of depression: systematic review and meta-analysis

Objective To determine the efficacy of psilocybin as an antidepressant compared with placebo or non-psychoactive drugs.

Design Systematic review and meta-analysis.

Data sources Five electronic databases of published literature (Cochrane Central Register of Controlled Trials, Medline, Embase, Science Citation Index and Conference Proceedings Citation Index, and PsycInfo) and four databases of unpublished and international literature (ClinicalTrials.gov, WHO International Clinical Trials Registry Platform, ProQuest Dissertations and Theses Global, and PsycEXTRA), and handsearching of reference lists, conference proceedings, and abstracts.

Data synthesis and study quality Information on potential treatment effect moderators was extracted, including depression type (primary or secondary), previous use of psychedelics, psilocybin dosage, type of outcome measure (clinician rated or self-reported), and personal characteristics (eg, age, sex). Data were synthesised using a ....

Mike Clarke , Marina Metaxa , University Of Oxford Nuffield Department Medicine , Department For Continuing Education , International Prospective Register Of Systematic , International Clinical Trials Registry Platform , University Of Oxford Msc , Athina Marina Metaxa , Am Metaxa , Cochrane Central Register , Controlled Trials , Science Citation Index , Conference Proceedings Citation Index , Clinical Trials Registry Platform , Proquest Dissertations , Theses Global , International Prospective Register , Systematic Reviews , Cochrane Handbook , Oxford Nuffield Department , Primary Care Health Sciences , Continuing Education , Open Access , Creative Commons Attribution Non Commercial ,

E-cigarette use vs. nicotine replacement therapy leads to higher quit rates

E-cigarette use vs. nicotine replacement therapy leads to higher quit rates
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Byisabella Hornick , Jamie Hartmann Boyce , Kristen Dowd , Health Sciences At University Of Massachusetts Amherst , Cochrane Tobacco Addiction Group Specialized Register , International Clinical Trials Registry Platform , School Of Public Health , Cochrane Database , Public Health , Health Sciences , Massachusetts Amherst , Cochrane Tobacco Addiction Group , Specialized Register , Cochrane Central Register , Controlled Trials , Clinical Trials Registry Platform ,

Global Endobronchial Valves Market Size Predicted to Reach USD 284.76 Million By 2032, Growing at 5.9% CAGR: Report by Polaris Market Research

/PRNewswire/ A latest research report [115+] pages with 360-Degree visibility, titled "Endobronchial Valves Market Share, Size, Trends, Industry Analysis. ....

South Africa , Saudi Arabia , United States , South Korea , New York , Asia Pacific , Clinical Research Center , Pulmonx Corporation , International Clinical Trials Registry Platform , Broncus Medical Inc , World Health Organization , Pneumrx Inc , Pages Research Report Inclusion Of Updated , Aspiration Inc , Drug Administration , Surgery Center , Endostim Inc , Boston Scientific Corporation , Polaris Market Research , American Lung Association , Olympus Corporation , International Ltd , Valves Market Share , Industry Analysis Report , Product Type , End User ,

GHTC submits written input to the WHO clinical trial guidance public consultation

GHTC submitted the following comments in response to a World Health Organization (WHO) public consultation seeking input on its draft guidance for best practices for clinical trials. ....

International Clinical Trials Registry Platform , African Medicines Agency , Journal Of The International , World Health Organization , Toolkit For Research , World Health Assembly , Development Of Pediatric Antiretroviral Drugs , Global Health Technologies Coalition , Clinical Trials Registry Platform , African Medicines Regulatory Harmonization , African Medicines , Breastfeeding Individuals , Clinical Trials , International Council , Technical Requirements , Human Use , Pediatric Antiretroviral Drugs , Rome Action Plan , High Level Dialogue ,

Meta-Analysis Points to Most Effective Topical Treatments for Atopic Dermatitis

Pimecrolimus, tacrolimus, and moderate-potency topical corticosteroids come out on top ....

Derekk Chu , International Clinical Trials Registry Platform , Mcmaster University , Atopic Dermatitis , Clinical Trials Registry Platform , Global Resource , Eczema Trials , Allergy Clin Immunol ,