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Nanotechnology Now - Press Release: Advanced nanoparticles provide new weapon to fight difficult cancers: Researchers use nanoparticles to deliver a bacterially derived compound that targets the STING pathway to suppress tumor growth and metastasis by disrupting blood vessels and stimulating immune response

Nanotechnology Now - Press Release: Advanced nanoparticles provide new weapon to fight difficult cancers: Researchers use nanoparticles to deliver a bacterially derived compound that targets the STING pathway to suppress tumor growth and metastasis by disrupting blood vessels and stimulating immune response
nanotech-now.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from nanotech-now.com Daily Mail and Mail on Sunday newspapers.

University Of Chicago , United States , Wenxin Zheng , Yang Xin Fu , Andras Piffko , Matt Wood , Sirui Li , Chuanhui Han , Xiaomin Jiang , Jiaai Wang , Kaiting Yang , Jason Bugno , Wenbo Han , Liangliang Wang , Ziwan Xu , Xiaona Huang , Wenbin Lin , Ralph Weichselbaum , Hua Liang , Ludwig Foundation , Coordination Pharmaceuticals , German Research Foundation , University Of North Carolina At Chapel Hill , Wave Inc , Tsinghua University , Danielk Ludwig Distinguished Service Professor ,

Errant DNA boosts immunotherapy effectiveness


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IMAGE: A UT Southwestern study discovered the molecular mechanism by which tumors defective in DNA mismatch repair respond to immunotherapy. This illustration depicts how cells use a programmed mismatch repair deficiency-activated.
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Credit: Illustration by Yipin Wu
DALLAS - Dec. 17, 2020 - DNA that ends up where it doesn t belong in cancer cells can unleash an immune response that makes tumors more susceptible to immunotherapy, the results of two UT Southwestern studies indicate. The findings, published online today in
Cancer Cell, suggest that delivering radiation - which triggers DNA release from cells - before immunotherapy could be an effective way to fight cancers that are challenging to treat. ....

United States , Junqiu Zhang , Eugene Frenkel , Longchao Liu , Zhenhua Ren , Anthonyj Davis , Janice Ortega , Qihuang Jin , Tao Wang , Yong Liang , Xuezhi Cao , Ralphb Rogers , Huiming Lu , Axiang Chen , Zhida Liu , Jiankun Zhu , Junhong Guan , Reecea Overcash Jr , Mary Nell , Yang Xin Fu , Liya Gu , Chuanhui Han , Hongyi Zhang , Zhijianj Chen , Jerryw Shay , Jian Qiao ,