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Unlocking radiation resistance: Missing protein key to suppressing cancer-fighting cells

A new study finds that radiation therapy (RT) suppresses a key protein called bone morphogenetic protein and activin membrane-bound inhibitor (BAMBI) and activates immune suppressive cells. ....

Chuan He , United States , Nordrhein Westfalen , University Of Chicago , Sean Pitroda , Stevenj Chmura , Wei Si , Xiaona Huang , Chuangyu Wen , Hua Laura Liang , Jason Bugno , Linda Zhang , Xiaoyang Dou , Ralph Weichselbaum , Kaiting Yang , Ainhoa Arina , Liangliang Wang , Jiaai Wang , Xianbin Yu , Dapeng Chen , Shandong First Medical University , Danielk Ludwig Distinguished Service Professor , University Of Chicago Medical Center , Ludwig Cancer Research Foundation , National Institutes Of Health , University Of Chicago Medicine Comprehensive Cancer Center ,

Novel therapeutic target overcomes resistance

<p>UChicago Medicine researchers discover that restoring BAMBI to normal levels in immune suppressive cells can overcome resistance to radiation therapy.</p>
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United States , University Of Chicago , Chuan He , Nordrhein Westfalen , Nano Proteagen , Xianbin Yu , Wei Si , Hua Laura Liang , Ainhoa Arina , Ralph Weichselbaum , Jiaai Wang , Xiaoyang Dou , Nkmax America , Xiaona Huang , Dapeng Chen , Stevenj Chmura , Jason Bugno , Liangliang Wang , Chuangyu Wen , Kaiting Yang , Sean Pitroda , Linda Zhang , Reflexion Pharmaceuticals , University Medical Center Hamburg , Shandong Academy Of Medical Sciences , Method Of Research ,

New Therapy Target Surmounts Radiation Resistance

New Therapy Target Surmounts Radiation Resistance
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Chuan He , University Of Chicago , United States , Nordrhein Westfalen , Hua Laura Liang , Kaiting Yang , Ainhoa Arina , Jason Bugno , Chuangyu Wen , Dapeng Chen , Linda Zhang , Stevenj Chmura , Ralph Weichselbaum , Jiaai Wang , Liangliang Wang , Xiaona Huang , Xianbin Yu , Xiaoyang Dou , Sean Pitroda , Wei Si , Ludwig Cancer Research Foundation , Shandong First Medical University , Danielk Ludwig Distinguished Service Professor , Shandong Academy Of Medical Sciences , University Medical Center Hamburg , Research Assistant Professor ,

Novel Nanotechnology Shows Efficacy in Mouse Models of Multiple Cancers

A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers. ....

Wenbin Lin , Laura Thomsonoct , Kaiting Yang , Ralph Weichselbaum , Ludwig Center At Chicago , Chicago Center Weichselbaum , A Ludwig Cancer Research , Ludwig Cancer Research , Co Director Ralph Weichselbaum , Ludwig Center , Chicago Center Co Director ,

Ludwig Chicago nanotechnology induces therapeutic immune responses against multiple types of tumors

A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers. ....

Wenbin Lin , Kaiting Yang , Ralph Weichselbaum , Emily Henderson , Ludwig Center At Chicago , Lab Diagnostics Automation , Chicago Center Weichselbaum , Lab Diagnostics Automation Industry , A Ludwig Cancer Research , Ludwig Cancer Research , Co Director Ralph Weichselbaum , Ludwig Center , Chicago Center Co Director , Automation Industry Focus , Blood Vessels , Cancer Therapy , Pancreatic Cancer , Pd L1 ,