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Single protein elicits multilineage reprogramming of astrocytes in adult mouse brains

A single protein can reverse the developmental clock on adult brain cells called astrocytes, morphing them into stem-like cells that produce neurons and other cell types, UT Southwestern researchers report in a PNAS study. ....

Lei Wang , Chun Li Zhang , Yang Xin Fu , Chuanhui Han , Emily Henderson , Peter Odonnell Jr , Boxun Li , Yuhua Zou , Sergio Cananzi , Yunjia Zhang , Brain Institute , Reproductive Biology Sciences , Genomics Institute , Lyda Hill Department Of Bioinformatics , Duke University , Tsinghua University , Ida Green Center , Molecular Biology , Petero Donnell , Gary Hon , Assistant Professor , Lyda Hill Department , Beijing Genomics Institute , Peking University , Molecular Biology , Stem Cells ,