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Bariatric surgery significantly reduced major adverse liver outcomes in MASH cirrhosis

At 15 years of follow-up, metabolic surgery “was not only safe” but also significantly reduced major adverse liver outcomes and decompensation in patients with metabolic dysfunction-associated steatohepatitis and compensated cirrhosis.“Previous studies suggested excellent clinical outcomes in patients with MASH and fibrosis stages 1 to 3 with improvement in both cardiac and ....

United States , Heather Biele , Bymonica Stonehill , Naim Alkhouri , Arizona Liver Health , Cleveland Clinical Health System , Advancing Long Term ,

Elafibranor has 'significant, sustained treatment benefit' in PBC through 78 weeks

Elafibranor sustained biochemical response through week 78 in patients with primary biliary cholangitis and has a “potential beneficial effect” on itch-related quality of life, according to late-breaking data presented at EASL Congress.“There is a major unmet need for a primary biliary cholangitis (PBC) treatment that effectively targets the biochemical indicators of disease ....

United States , Christelle Huguet , Bymonica Stonehill , Andrease Kremer , Heather Biele , Christopherl Bowlus , University Hospital Zurich , Uc Davis Health , Liver Meeting ,

A catered low-fat, high-fiber diet 'new, hopeful option' to manage Crohn's disease

WASHINGTON — Patients with Crohn’s disease who ate a catered low-fat, high-fiber diet for 8 weeks experienced improvements in symptoms, inflammation and quality of life vs. those offered counseling alone, researchers reported.
“We know that most patients with Crohn’s disease seek dietary counseling and ask their physicians about the foods they should consume,” Hajar ....

United States , Bymonica Stonehill , Heather Biele , Hajar Hazime , Mariat Abreu , Miller School Of Medicine , Abreu Lab , Colitis Center , Miller School , Digestive Disease Week , Disease Activity ,

Entyvio effective in pediatric IBD, 'should be included in our treatment paradigm'

WASHINGTON — Entyvio is “safe and effective” for maintaining sustained steroid-free remission at 1 year in children with inflammatory bowel disease, more so in those with ulcerative colitis vs. Crohn’s disease, according to a researcher.
“We know that children with inflammatory bowel disease, compared to adults, can have a more severe disease phenotype that is ....

United States , Heather Biele , Ronene Stein , Bymonica Stonehill , Takeda Pharmaceuticals , University Of Pennsylvania Perelman School Medicine , Pennsylvania Perelman School , Digestive Disease Week , Pediatric Crohn , Disease Activity Index , Pediatric Ulcerative Colitis Activity Index ,

Noninvasive tests identify candidates for Rezdiffra, predict response in patients with MASH

WASHINGTON — Researchers have determined that several noninvasive tests could help identify candidates for treatment with Rezdiffra, as well as predict response, in metabolic dysfunction-associated steatohepatitis.
“We wanted to identify if we could predict response to treatment among patients treated with resmetirom,” Rohit Loomba, MD, MHSc, professor of medicine and chief of ....

United States , San Diego , Bymonica Stonehill , Heather Biele , Rohit Loomba , University Of California , Research Center , Madrigal Pharmaceuticals , School Of Medicine , Digestive Disease Week ,