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Hyperspectral Imaging Allows the Simultaneous Measurement of Fluorophores | Features | Jul/Aug 2023

Hyperspectral Imaging Allows the Simultaneous Measurement of Fluorophores | Features | Jul/Aug 2023
photonics.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from photonics.com Daily Mail and Mail on Sunday newspapers.

United States , Montana State University , Roger Tsien , Osamu Shimomura , Martin Chalfie , Merrilee Thomas , Gabor Kemeny , Slater Kirk , National Center , Eli Lilly Company , Translational Sciences , Nobel Prize , Middleton Spectral , Montana Molecular , Middleton Spectral Vision , Rand Swanson , Thom Hughes , Assay Guidance , Eli Lilly , Advancing Translational , Biol Cell , Discovery Today , Soc Rev ,

John M. Maloney - Research Interest: Thin Film Patterns

John M. Maloney - Research Interest: Thin Film Patterns
maloney.org - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from maloney.org Daily Mail and Mail on Sunday newspapers.

Manoj Chaudhury , Enrique Cerda , Anshutosh Sharma , Scripta Materialia , Adam Zeiger , Toyoichi Tanaka , Acta Materialia , Leonard Schwarz , Indian Institute Of Technology , Annie Viallet At Joseph Fourier University , University Of Delaware , Maloney Home Page , Thin Film , From Science , Ali Argon , Materials Science , Joseph Fourier University , Rev Lett , Physics Letters , Mech Phys Solids , Funct Materials , Solid Films , Indian Institute , Colloid Interface Sci , Biol Cell ,

Type 1 diabetes

Type 1 diabetes is a chronic disease caused by autoimmune destruction of pancreatic
β cells. Individuals with type 1 diabetes are reliant on insulin for survival. Despite
enhanced knowledge related to the pathophysiology of the disease, including interactions
between genetic, immune, and environmental contributions, and major strides in treatment
and management, disease burden remains high. Studies aimed at blocking the immune
attack on β cells in people at risk or individuals with very early onset type 1 diabetes
show promise in preserving endogenous insulin production. ....

United Kingdom , Nordrhein Westfalen , Sri Lanka , Southern Ostrobothnia , United States , North Yorkshire , Cardiovasc Diabetol , Pediatr Nephrol , J Clin Endocrinol , Nat Genet , Hosseini Fard , Al Taji , Adolesc Nutr , American Diabetes Association Professional Pratice Committee , American Diabetes Association Professional Practice Committee , Market Research , Id Exchange , Health Promot Perspect , National Youth Tobacco , Steno Diabetes Center Copenhagen , Endocrine Society , European Association For The Study Of Diabetes , International Diabetes Federation Atlas , Diabetes Study Group , Lancet Child Adolesc Health , American Diabetes Association ,

Frontiers | The One That Got Away: How Macrophage-Derived IL-1β Escapes the Mycolactone-Dependent Sec61 Blockade in Buruli Ulcer

Buruli ulcer (BU), caused by Mycobacterium ulcerans, is a devastating necrotizing skin disease. Key to its pathogenesis is mycolactone, the exotoxin virulence factor that is both immunosuppressive and cytotoxic. The discovery that the essential Sec61 translocon is the major cellular target of mycolactone explains much of the disease pathology, including the immune blockade. Sec61 inhibition leads to a loss in production of nearly all cytokines from monocytes, macrophages, dendritic cells and T cells, as well as antigen presentation pathway proteins and costimulatory molecules. However, there has long been evidence that the immune system is not completely incapable of responding to M. ulcerans infection. In particular, IL-1beta was recently shown to be present in BU lesions, and to be induced from M. ulcerans-exposed macrophages in a mycolactone-dependent manner. This has important implications for our understanding of BU, showing that mycolactone can act as the “second signal” for ....

United States , Western Australia , Le Bon , Scandj Rheumatol , Rheumatol Oxford , M Ulcerans Mycolactone Cytotoxicity , Pedrosaj Mycolactone , Waal Malefyt , Sarpong Duah , Rajko Reljic , Van Haver , Van Puyenbroeck , Thyet Mycolactone , Mycolactone Polyketide Synthases , Prof Pamela Small University Of Knoxville , Riverside Research Ethics Committee , Kennedy Institute Trustees , Wellcome Trust Investigator Award In Science , Streptomycin For Limited Buruli Ulcer Lesions , Prof Yoshito Kishi Harvard University , Lancet Glob Health , Dr Justice Boakye Appiah St George University London , West Africa , Immune Response , Buruli Ulcer , Wellcome Trust Investigator Award ,