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Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer

Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer
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Store Fat or Burn It? Targeting a Single Protein Flips the Switch

Store Fat or Burn It? Targeting a Single Protein Flips the Switch
As obesity becomes a growing issue worldwide – nearly tripling over the last-half century – scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain.
As reported in
Nature Metabolism on Feb. 18, 2021, UCSF’s Davide Ruggero, PhD, and colleagues found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet. ....

United States , Yasuo Oguri , Davide Ruggero , Almal Burlingame , Alma Burlingame , Kenji Ikeda , Harrisonj Tom , Ryanm Gill , Hieu Vu , Shingo Kajimura , Supna Nair , Chaojun Yang , Ralphj Deberardinis , Cancer Research , Effector Therapeutics Inc , Ut Southwestern Medical Center , University Of Pennsylvania Perelman School Medicine , National Institutes Of Health , Nature Metabolism , Helen Diller Family Chair , Basic Cancer Research , Perelman School , National Institutes , American Cancer Society , American Cancer Society Research Professor Award , ஒன்றுபட்டது மாநிலங்களில் ,

Is this one protein responsible for weight gain?

Credit: UCSF
As obesity becomes a growing issue worldwide nearly tripling over the last-half century scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain.
As reported in Nature Metabolism on Feb. 18, 2021, UCSF’s Davide Ruggero, Ph.D., and colleagues found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet. ....

United States , Yasuo Oguri , Davide Ruggero , Almal Burlingame , Alma Burlingame , Kenji Ikeda , Harrisonj Tom , Ryanm Gill , Hieu Vu , Shingo Kajimura , Supna Nair , Chaojun Yang , Ralphj Deberardinis , Cancer Research , Effector Therapeutics Inc , Ut Southwestern Medical Center , University Of Pennsylvania Perelman School Medicine , National Institutes Of Health , Nature Metabolism , Helen Diller Family Chair , Basic Cancer Research , Perelman School , National Institutes , American Cancer Society , American Cancer Society Research Professor Award , ஒன்றுபட்டது மாநிலங்களில் ,

Store fat or burn it? Targeting a single protein flips the switch

As obesity becomes a growing issue worldwide - nearly tripling over the last-half century - scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsize role in weight gain. ....

San Francisco , United States , Yasuo Oguri , Davide Ruggero , Almal Burlingame , Alma Burlingame , Kenji Ikeda , Harrisonj Tom , Ryanm Gill , Hieu Vu , Shingo Kajimura , Supna Nair , Chaojun Yang , Ralphj Deberardinis , University Of California , Effector Therapeutics Inc , University Of Pennsylvania Perelman School Medicine , National Institutes Of Health , Cancer Research , Ut Southwestern Medical Center , Nature Metabolism , Helen Diller Family Chair , Basic Cancer Research , Perelman School , National Institutes , American Cancer Society ,

Store Fat or Burn It? Targeting a Single Protein Flips Switch

As obesity becomes a growing issue worldwide - nearly tripling over the last-half century - scientists are trying to gain a better understanding of the. ....

San Francisco , United States , Yasuo Oguri , Davide Ruggero , Almal Burlingame , Alma Burlingame , Kenji Ikeda , Harrisonj Tom , Ryanm Gill , Hieu Vu , Shingo Kajimura , Supna Nair , Chaojun Yang , Ralphj Deberardinis , Cancer Research , University Of California , Effector Therapeutics Inc , Ut Southwestern Medical Center , University Of Pennsylvania Perelman School Medicine , National Institutes Of Health , Nature Metabolism , Helen Diller Family Chair , Basic Cancer Research , Perelman School , National Institutes , American Cancer Society ,