“Metabolic Reprogramming in Human Cancer” Presented by: Ralph J. DeBerardinis, MD, PhD Professor, Children’s Medical Center Research Institute at UT Southwestern Medical Center Sponsor: Maria Laura Avantaggiati, MD About the Speaker: Dr. Ralph DeBerardinis joined the faculty of UT Southwestern Medical Center in 2008 and joined the Children’s Medical Center Research Institute at UTSW (CRI) […]
Store Fat or Burn It? Targeting a Single Protein Flips the Switch
As obesity becomes a growing issue worldwide – nearly tripling over the last-half century – scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain.
As reported in
Nature Metabolism on Feb. 18, 2021, UCSF’s Davide Ruggero, PhD, and colleagues found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet.
Credit: UCSF
As obesity becomes a growing issue worldwide nearly tripling over the last-half century scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsized role in weight gain.
As reported in Nature Metabolism on Feb. 18, 2021, UCSF’s Davide Ruggero, Ph.D., and colleagues found that mice in which activity of a protein called eIF4E is diminished, either genetically or pharmaceutically, gain only half the weight of other mice, even if all the mice eat a high-fat diet.
As obesity becomes a growing issue worldwide - nearly tripling over the last-half century - scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsize role in weight gain.
As obesity becomes a growing issue worldwide - nearly tripling over the last-half century - scientists are trying to gain a better understanding of the.