Live Breaking News & Updates on Agilent Zorbax

Stay updated with breaking news from Agilent zorbax. Get real-time updates on events, politics, business, and more. Visit us for reliable news and exclusive interviews.

Facilitated buccal insulin delivery via HIP approach


is the amount of free insulin in the supernatant.
Partition Coefficient
The partition coefficients of insulin, C1, and C2 were also determined. Briefly, 1 mg of insulin or the freeze-dried powder of C1 or C2 (equivalent to 1 mg insulin) was added to 1 mL of octanol/water (1:1) and incubated at 25°C for 24 h with vigorous stirring (600 rpm). After 24 h, the samples were centrifuged at 15,602 ×
g for 15 min at 4°C. Finally, the aqueous and oil phases were separated, collected, and analyzed using RP-HPLC as previously described. The partition coefficient was determined as follows:
(2)
denotes the concentration of insulin in the aqueous phase at equilibrium. ....

Kyongsang Bukto , South Korea , United States , United Kingdom , Kangwon Do , Uppsala Lan , Mashonaland East , Kyonggi Do , Republic Of Korea , Santa Clara , Carl Zeiss Meditec , Agilent Technologies Inc , Nanobrook Zetapals Brookhaven Instruments Corp , Tm Deep Red Life Technologies Inc , Dako North America Inc , Hanil Science Industrial Co , Sakura Finetek United States Inc , Scientific Co Ltd , Aetos Technologies Inc , Public Health England , Corning Inc , Thermo Fisher Scientific Inc , Millipore Corporation , European Collection , Authenticated Cell Cultures , Hanil Science Industrial ,