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Control of external contaminants during CGT materials production

The quality of materials and reagents used in Cell and Gene Therapy (CGT) production processes plays avital role in determining both the product quality as well as therapeutic safety, and external contaminantsmust be strictly controlled. ....

Aimee Molineux , National Institute For Biological Standards , Drug Administration , European Medicines Agency , International Conference On Harmonization , Sponsored Content , Gene Therapy , Tissue Engineered Products , Biological Origin , Gene Therapy Medicinal Products , European Collection , Authenticated Cell Cultures , Cell Line Characterization , Cell Lines Used , Cell Substrates , Viral Vaccines , Infectious Disease , Safety Evaluation , Biotechnology Products Derived , Cell Lines , Virus Safety Evaluation , Biotechnological Investigational Medicinal , Medicines Agency , Host Cell Protein , National Institute , Biological Standards ,

NCOA4-mediated ferroptosis in bronchial epithelial cells

Investigating the relationship between macrophage polarization and ferroptosis in COPD emphysema ....

United States , Qian Men , Eteläuomen Läi , Merck Millipore , Buxco Electronics Ltd , National Collection Of Authenticated Cell Cultures , Changzhou Kawensi Experimental Animal Co Ltd , Jiangsu Provincial Center , Beyotime Institute Of Biotechnology , Chi Scientific , Biological Industries , Thermo Fisher Scientific , National Collection , Authenticated Cell Cultures , Wuxi People , Jiangsu Province Institutional Animal Care , Use Committee , Jiangsu Province , Disease Control , Buxco Electronics , Beyotime Institute , Electron Microscopy , Image Pro Plus , Prime Script , Sangon Biotech , Premix Ex Taq ,

Stichoposide C exerts anticancer effects on ovarian cancer

Stichoposide C (STC) is a triterpene glycoside isolated from Thelenota ananas, was previously demonstrated to wide spectrum of anticancer effects. ....

United States , Eteläuomen Läi , South China Sea , Brunei General , Shanghai Jiao Tong University School Of Medicine , C Shanghai University Of Traditional Chinese Medicine , Key Laboratory Of Oncogenes , Renji Hospital Ethics Committee Ethic , Renji Hospital Ethics Committee , National Collection Of Authenticated Cell Cultures Shanghai , Research Center , Shanghai Key Laboratory Of Gynecologic Oncology , Shanghai Jiao Tong University , Hanbio Technology , Shanghai Superbk Laboratory Animal Corp , Beyotime Institute Of Biotechnology , Woody Island , South China , Marine Drugs , State Key Laboratory , Related Genes , Renji Hospital , Shanghai Jiao Tong , Shanghai University , Traditional Chinese Medicine , Cell Counting ,

Osteoclasts and Glucose Uptake-Related Insulin Resistance

Osteoclasts and Glucose Uptake-Related Insulin Resistance
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United States , Resistin Quantikine , Lipofectamine Rnai , National Collection Of Authenticated Cell Cultures Shanghai , Animal Care Committee Of Shanghai Gongli Hospital , Tiangen Biotech Co , Animals National Research Council , National Collection , Authenticated Cell Cultures , Life Technologies , Animal Care Committee , Shanghai Gongli , Guiding Principles , National Research Council , Quantitative Real Time Polymerase Chain Reaction , Detection System , Linked Immunosorbent Assay , Mouse Resistin Quantikine , ஒன்றுபட்டது மாநிலங்களில் , தேசிய சேகரிப்பு , அங்கீகரிக்கப்பட்டது செல் கலாச்சாரங்கள் , வாழ்க்கை தொழில்நுட்பங்கள் , விலங்கு பராமரிப்பு குழு , வழிகாட்டுதல் ப்ரிந்ஸிபல்ஸ் , தேசிய ஆராய்ச்சி சபை , கண்டறிதல் அமைப்பு ,

Facilitated buccal insulin delivery via HIP approach

is the amount of free insulin in the supernatant.
Partition Coefficient
The partition coefficients of insulin, C1, and C2 were also determined. Briefly, 1 mg of insulin or the freeze-dried powder of C1 or C2 (equivalent to 1 mg insulin) was added to 1 mL of octanol/water (1:1) and incubated at 25°C for 24 h with vigorous stirring (600 rpm). After 24 h, the samples were centrifuged at 15,602 ×
g for 15 min at 4°C. Finally, the aqueous and oil phases were separated, collected, and analyzed using RP-HPLC as previously described. The partition coefficient was determined as follows:
(2)
denotes the concentration of insulin in the aqueous phase at equilibrium. ....

Kyongsang Bukto , South Korea , United States , United Kingdom , Kangwon Do , Uppsala Lan , Mashonaland East , Kyonggi Do , Republic Of Korea , Santa Clara , Carl Zeiss Meditec , Agilent Technologies Inc , Nanobrook Zetapals Brookhaven Instruments Corp , Tm Deep Red Life Technologies Inc , Dako North America Inc , Hanil Science Industrial Co , Sakura Finetek United States Inc , Scientific Co Ltd , Aetos Technologies Inc , Public Health England , Corning Inc , Thermo Fisher Scientific Inc , Millipore Corporation , European Collection , Authenticated Cell Cultures , Hanil Science Industrial ,